Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 3/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.32 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28909219 | 1.00 | CFTR (0.39) | CFTRIRAK4HCRTR1HCRTR2MAPT | |
| SCHEMBL25687424 | 1.00 | CFTR (0.39) | CFTRIRAK4HCRTR1HCRTR2MAPT | |
| SCHEMBL23958644 | 0.92 | CFTR (0.36) | CFTRMAPTCNR2ROCK2ROCK1 | |
| SCHEMBL30007924 | 0.92 | CFTR (0.36) | CFTRMAPTCNR2ROCK2ROCK1 | |
| SCHEMBL23958706 | 0.92 | CFTR (0.36) | CFTRMAPTCNR2ROCK2ROCK1 | |
| SCHEMBL25687411 | 0.92 | CFTR (0.36) | CFTRMAPTCNR2ROCK2ROCK1 | |
| SCHEMBL23958761 | 0.91 | CFTR (0.35) | CFTRIRAK4MAPTCNR2RIPK1 | |
| SCHEMBL23958708 | 0.91 | CFTR (0.35) | CFTRIRAK4MAPTCNR2RIPK1 | |
| SCHEMBL30007745 | 0.90 | CFTR (0.34) | CFTRMAPTCNR2RIPK1ROCK2 | |
| SCHEMBL25686209 | 0.90 | CFTR (0.34) | CFTRMAPTCNR2RIPK1ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115461336-A | RSV inhibiting 3-substituted quinoline and cinnoline derivatives | 爱尔兰詹森科学公司 | 2022-12-09 | — | — | CN | disclosed |