Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 4/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ULK1 | O75385 | 1/20 | 0.32 |
| ▸ | PTGFR | P43088 | 2/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25687212 | 1.00 | CFTR (0.36) | CFTRGABRA5KDM4EALDH1A1NPSR1 | |
| SCHEMBL25240950 | 0.94 | CFTR (0.37) | CFTRGABRA5KDM4EALDH1A1NPSR1 | |
| SCHEMBL30007175 | 0.94 | CFTR (0.37) | CFTRGABRA5KDM4EALDH1A1NPSR1 | |
| SCHEMBL25686191 | 0.94 | CFTR (0.37) | CFTRGABRA5KDM4EALDH1A1NPSR1 | |
| SCHEMBL30007224 | 0.91 | CFTR (0.36) | CFTRGABRA5KDM4EALDH1A1NPSR1 | |
| SCHEMBL23958781 | 0.91 | CFTR (0.36) | CFTRGABRA5KDM4EALDH1A1NPSR1 | |
| SCHEMBL23958750 | 0.91 | CFTR (0.36) | CFTRGABRA5KDM4EALDH1A1NPSR1 | |
| SCHEMBL23958696 | 0.91 | SSTR5 (0.32) | CFTRGABRA5MAPT | |
| SCHEMBL30007076 | 0.91 | SSTR5 (0.32) | CFTRGABRA5MAPT | |
| SCHEMBL25687279 | 0.91 | SSTR5 (0.32) | CFTRGABRA5MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115461336-A | RSV inhibiting 3-substituted quinoline and cinnoline derivatives | 爱尔兰詹森科学公司 | 2022-12-09 | — | — | CN | disclosed |