Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 7/20 | 0.73 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | DHODH | Q02127 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL291479 | 1.00 | PDE5A (0.73) | PDE5AMAPTKDM4EALDH1A1DHODH | |
| SCHEMBL290905 | 0.89 | PDE5A (0.72) | PDE5AMAPTKDM4EALDH1A1DHODH | |
| SCHEMBL29831857 | 0.89 | PDE5A (0.72) | PDE5AMAPTKDM4EALDH1A1DHODH | |
| SCHEMBL290598 | 0.88 | PDE5A (0.71) | PDE5AMAPTKDM4EALDH1A1DHODH | |
| SCHEMBL290698 | 0.88 | PDE5A (0.75) | PDE5AMAPTKDM4EALDH1A1DHODH | |
| SCHEMBL290844 | 0.85 | PDE5A (1.00) | PDE5AMAPTKDM4EALDH1A1DHODH | |
| SCHEMBL6068376 | 0.83 | MAPT (0.54) | PDE5AMAPTKDM4EALDH1A1DHODH | |
| SCHEMBL2681053 | 0.81 | PDE5A (0.88) | PDE5AMAPTKDM4EALDH1A1DHODH | |
| SCHEMBL290788 | 0.81 | PDE5A (0.91) | PDE5AMAPTKDM4EALDH1A1DHODH | |
| SCHEMBL29832145 | 0.81 | PDE5A (0.91) | PDE5AMAPTKDM4EALDH1A1DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4572765-A1 | USE OF A THERAPEUTIC AGENT WITH PHOSPHODIESTERASE-7 INHIBITORY ACTIVITY FOR THE TREATMENT AND PREVENTION OF DISEASES ASSOCIATED WITH CHRONIC FATIGUE, EXHAUSTION AND/OR EXERTIONAL INTOLERANCE | Mitodicure GmbH (DE) | 2025-06-25 | — | — | EP | disclosed |
| WO-2024038089-A1 | USE OF A THERAPEUTIC AGENT WITH PHOSPHODIESTERASE-7 INHIBITORY ACTIVITY FOR THE TREATMENT AND PREVENTION OF DISEASES ASSOCIATED WITH CHRONIC FATIGUE, EXHAUSTION AND/OR EXERTIONAL INTOLERANCE | MITODICURE GMBH (DE) | 2024-02-22 | — | — | WO | disclosed |
| CN-115192711-A | Use of PDE7 inhibitors for the treatment of movement disorders | 奥默罗斯公司 | 2022-10-18 | — | — | CN | disclosed |