Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 3/20 | 0.38 |
| ▸ | CNR2 | P34972 | 4/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23958768 | 1.00 | CFTR (0.38) | CFTRCNR2TRPV1CYP17A1CYP3A4 | |
| SCHEMBL25686518 | 1.00 | CFTR (0.38) | CFTRCNR2TRPV1CYP17A1CYP3A4 | |
| SCHEMBL23958853 | 1.00 | CFTR (0.38) | CFTRCNR2TRPV1CYP17A1CYP3A4 | |
| SCHEMBL23930208 | 0.91 | CFTR (0.35) | CFTRCNR2TRPV1FPR2SCN9A | |
| SCHEMBL25689065 | 0.85 | CFTR (0.36) | CFTRCNR2TRPV1CYP17A1CYP3A4 | |
| SCHEMBL25230841 | 0.83 | CFTR (0.35) | CFTRCNR2TRPV1CNR1L3MBTL1 | |
| SCHEMBL23930046 | 0.82 | CFTR (0.38) | CFTRCNR2CYP3A4CNR1L3MBTL1 | |
| SCHEMBL23958625 | 0.82 | CFTR (0.39) | CFTRCNR2CYP3A4CNR1L3MBTL1 | |
| SCHEMBL30007072 | 0.82 | CFTR (0.38) | CFTRCNR2CYP3A4CNR1L3MBTL1 | |
| SCHEMBL25285421 | 0.82 | CFTR (0.38) | CFTRCNR2CYP3A4CNR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4139293-A1 | RSV INHIBITING 3-SUBSTITUTED QUINOLINE AND CINNOLINE DERIVATIVES | Janssen Sciences Ireland Unlimited Company (IE) | 2023-03-01 | — | — | EP | disclosed |
| CN-115461336-A | RSV inhibiting 3-substituted quinoline and cinnoline derivatives | 爱尔兰詹森科学公司 | 2022-12-09 | — | — | CN | disclosed |