SCHEMBL30007222 — predicted protein targets

Predicted protein targets (top 14)

	gene	UniProt	supporting neighbours	confidence
▸	CFTR	P13569	3/20	0.38

▸	GRM2	Q14416	1/20	0.37

▸	ACACB	O00763	2/20	0.35

▸	ACACA	Q13085	2/20	0.35

▸	MMP13	P45452	1/20	0.34

▸	CKS1B	P61024	1/20	0.34

▸	SKP1	P63208	1/20	0.34

▸	SKP2	Q13309	1/20	0.34

▸	RORC	P51449	4/20	0.34

▸	MMP8	P22894	4/20	0.33

▸	MMP3	P08254	2/20	0.33

▸	NTMT1	Q9BV86	1/20	0.33

▸	DRD2	P14416	1/20	0.33

▸	LATS1	O95835	1/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL25686935	1.00	CFTR (0.38)	CFTRGRM2ACACBACACAMMP13
SCHEMBL25278726	0.89	CFTR (0.38)	CFTRCKS1BSKP1SKP2
SCHEMBL23958684	0.87	CFTR (0.41)	CFTRGRM2CKS1BSKP1SKP2
SCHEMBL25686536	0.85	CFTR (0.42)	CFTRGRM2RORCLATS1
SCHEMBL25687164	0.83	CFTR (0.36)	CFTRGRM2ACACBACACAMMP13
SCHEMBL30471289	0.82	ACACB (0.36)	GRM2ACACBACACADRD2
SCHEMBL23958725	0.82	ACACB (0.36)	GRM2ACACBACACADRD2
SCHEMBL23958748	0.81	CFTR (0.33)	CFTR
SCHEMBL23958586	0.81	CFTR (0.33)	CFTR
SCHEMBL25686936	0.81	CFTR (0.33)	CFTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-115461336-A	RSV inhibiting 3-substituted quinoline and cinnoline derivatives	爱尔兰詹森科学公司	2022-12-09	—	—	CN	disclosed