Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 4/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
| ▸ | GCGR | P47871 | 3/20 | 0.31 |
| ▸ | GIPR | P48546 | 1/20 | 0.31 |
| ▸ | NAMPT | P43490 | 2/20 | 0.31 |
| ▸ | ULK1 | O75385 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25687385 | 1.00 | CFTR (0.36) | CFTRADORA2AADORA2BADORA1SCN9A | |
| SCHEMBL23958811 | 1.00 | CFTR (0.36) | CFTRADORA2AADORA2BADORA1SCN9A | |
| SCHEMBL25687310 | 0.93 | CFTR (0.39) | CFTRADORA2AADORA2BADORA1SCN9A | |
| SCHEMBL23958707 | 0.93 | CFTR (0.39) | CFTRADORA2AADORA2BADORA1SCN9A | |
| SCHEMBL25687415 | 0.87 | CFTR (0.40) | CFTRMAPT | |
| SCHEMBL25686197 | 0.86 | CFTR (0.40) | CFTRADORA2AADORA2BADORA1SCN9A | |
| SCHEMBL30211296 | 0.86 | CFTR (0.40) | CFTRADORA2AADORA2BADORA1SCN9A | |
| SCHEMBL25687518 | 0.86 | CFTR (0.40) | CFTRADORA2AADORA2BADORA1SCN9A | |
| SCHEMBL25284674 | 0.86 | CFTR (0.38) | CFTRSCN9AMAPT | |
| SCHEMBL25687304 | 0.86 | CFTR (0.38) | CFTRSCN9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115461336-A | RSV inhibiting 3-substituted quinoline and cinnoline derivatives | 爱尔兰詹森科学公司 | 2022-12-09 | — | — | CN | disclosed |