Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 16/20 | 0.76 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.60 |
| ▸ | DYRK3 | O43781 | 2/20 | 0.60 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.60 |
| ▸ | CDK2 | P24941 | 2/20 | 0.60 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.60 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.60 |
| ▸ | DYRK2 | Q92630 | 2/20 | 0.60 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.60 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.60 |
| ▸ | CDK9 | P50750 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23535622 | 1.00 | FYN (0.76) | FYNDYRK1ADYRK3CCNA2CDK2 | |
| SCHEMBL23535567 | 0.87 | FYN (0.72) | FYNDYRK1ADYRK3CCNA2CDK2 | |
| SCHEMBL30006704 | 0.87 | FYN (0.72) | FYNDYRK1ADYRK3CCNA2CDK2 | |
| SCHEMBL30521675 | 0.86 | FYN (1.00) | FYN | |
| SCHEMBL18613768 | 0.86 | FYN (1.00) | FYN | |
| SCHEMBL18613477 | 0.84 | FYN (1.00) | FYNDYRK1ADYRK3CCNA2CDK2 | |
| SCHEMBL30521738 | 0.84 | FYN (1.00) | FYNDYRK1ADYRK3CCNA2CDK2 | |
| SCHEMBL16331399 | 0.82 | FYN (0.72) | FYNDYRK1ADYRK3CCNA2CDK2 | |
| SCHEMBL20485664 | 0.81 | FYN (0.65) | FYNDYRK1ADYRK3CCNA2CDK2 | |
| SCHEMBL18613709 | 0.81 | FYN (1.00) | FYNDYRK1ADYRK3CCNA2CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120025336-A | LIN28 inhibitors and methods of use thereof | 加利福尼亚大学董事会 | 2025-05-23 | — | — | CN | disclosed |
| CN-115087657-B | LIN28 inhibitors and methods of use thereof | 加利福尼亚大学董事会 | 2025-01-21 | — | — | CN | disclosed |
| EP-4077332-A1 | INHIBITORS OF LIN28 AND METHODS OF USE THEREOF | The Regents of the University of California (US) | 2022-10-26 | — | — | EP | disclosed |