SCHEMBL30007633

SCHEMBL30007633

c1ccc(CN(Cc2ccccn2)Cc2cnccn2)nc1

nearest known ligand 0.63

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.63
SMN1; SMN2 Q16637 1/20 0.63
LIN28A Q9H9Z2 1/20 0.63
TDP1 Q9NUW8 1/20 0.63
CYP1A2 P05177 2/20 0.50
CYP3A4 P08684 2/20 0.50
CYP2C9 P11712 1/20 0.50
CYP2C19 P33261 1/20 0.50
CYP2D6 P10635 2/20 0.46
KCNA5 P22460 2/20 0.46
KCNN4 O15554 1/20 0.46
HSP90AA1 P07900 1/20 0.45
KMT2A Q03164 1/20 0.44
APP P05067 1/20 0.42
HRH1 P35367 2/20 0.41
HRH4 Q9H3N8 2/20 0.41
HRH3 Q9Y5N1 2/20 0.41
ALDH1A1 P00352 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16741951 0.86 CYP1A2 (0.47) MAPTSMN1; SMN2LIN28ATDP1CYP1A2
SCHEMBL138261 0.86 SMN1; SMN2 (0.83) MAPTSMN1; SMN2LIN28ATDP1CYP1A2
SCHEMBL30086190 0.84 SMN1; SMN2 (0.79) MAPTSMN1; SMN2LIN28ATDP1CYP1A2
SCHEMBL31533192 0.84 SMN1; SMN2 (0.79) MAPTSMN1; SMN2LIN28ATDP1CYP1A2
SCHEMBL30191149 0.84 SMN1; SMN2 (0.79) MAPTSMN1; SMN2LIN28ATDP1CYP1A2
SCHEMBL31533189 0.84 SMN1; SMN2 (0.79) MAPTSMN1; SMN2LIN28ATDP1CYP1A2
Hydrochloric Acid SCHEMBL9905725 0.84 SMN1; SMN2 (0.79) MAPTSMN1; SMN2LIN28ATDP1CYP1A2
SCHEMBL14357958 0.84 MAPT (0.79) MAPTSMN1; SMN2LIN28ATDP1CYP1A2
SCHEMBL31171174 0.84 SMN1; SMN2 (0.79) MAPTSMN1; SMN2LIN28ATDP1CYP1A2
SCHEMBL31533187 0.84 SMN1; SMN2 (0.79) MAPTSMN1; SMN2LIN28ATDP1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115197280-B Metal cobalt complex with photocatalytic carbon dioxide reduction activity and preparation method and application thereof 中国科学院理化技术研究所 2024-01-23 CN claimed
CN-115197280-A Metal cobalt complex with photocatalytic carbon dioxide reduction activity and preparation method and application thereof 中国科学院理化技术研究所 2022-10-18 CN claimed
CN-115197280-B Metal cobalt complex with photocatalytic carbon dioxide reduction activity and preparation method and application thereof 中国科学院理化技术研究所 2024-01-23 CN disclosed
CN-115197280-A Metal cobalt complex with photocatalytic carbon dioxide reduction activity and preparation method and application thereof 中国科学院理化技术研究所 2022-10-18 CN disclosed