Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 17/20 | 0.49 |
| ▸ | PPARA | Q07869 | 14/20 | 0.49 |
| ▸ | PPARG | P37231 | 4/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14146389 | 1.00 | PPARD (0.49) | PPARDPPARAPPARG | |
| SCHEMBL14146509 | 1.00 | PPARD (0.49) | PPARDPPARAPPARG | |
| SCHEMBL14146854 | 0.92 | PPARD (0.50) | PPARDPPARAPPARG | |
| SCHEMBL14146504 | 0.92 | PPARD (0.48) | PPARDPPARAPPARG | |
| SCHEMBL14146340 | 0.90 | PPARD (0.47) | PPARDPPARAPPARG | |
| SCHEMBL14146395 | 0.89 | PPARD (0.51) | PPARDPPARAPPARG | |
| SCHEMBL14146413 | 0.88 | PPARD (0.45) | PPARDPPARAPPARG | |
| SCHEMBL14146401 | 0.84 | MAPT (0.42) | PPARDPPARAPPARG | |
| SCHEMBL14146457 | 0.83 | PTPN1 (0.44) | PPARDPPARAPPARG | |
| SCHEMBL218478 | 0.82 | PPARA (0.36) | PPARDPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4337185-A1 | ELAFIBRANOR DERIVATIVES AGONISTS OF PPAR FOR USE IN THE TREATMENT OF SEPSIS | Genfit (FR) | 2024-03-20 | — | — | EP | claimed |
| EP-4337184-A1 | PPAR-AGONISTS FOR USE IN THE TREATMENT OF LIVER FAILURE | Genfit (FR) | 2024-03-20 | — | — | EP | claimed |
| WO-2022238445-A1 | PPAR-AGONISTS FOR USE IN THE TREATMENT OF LIVER FAILURE | GENFIT (FR) | 2022-11-17 | — | — | WO | claimed |
| WO-2022238448-A1 | ELAFIBRANOR DERIVATIVES AGONISTS OF PPAR FOR USE IN THE TREATMENT OF SEPSIS | GENFIT (FR) | 2022-11-17 | — | — | WO | claimed |
| EP-4337184-A1 | PPAR-AGONISTS FOR USE IN THE TREATMENT OF LIVER FAILURE | Genfit (FR) | 2024-03-20 | — | — | EP | disclosed |
| EP-4337185-A1 | ELAFIBRANOR DERIVATIVES AGONISTS OF PPAR FOR USE IN THE TREATMENT OF SEPSIS | Genfit (FR) | 2024-03-20 | — | — | EP | disclosed |
| WO-2022238445-A1 | PPAR-AGONISTS FOR USE IN THE TREATMENT OF LIVER FAILURE | GENFIT (FR) | 2022-11-17 | — | — | WO | disclosed |
| WO-2022238448-A1 | ELAFIBRANOR DERIVATIVES AGONISTS OF PPAR FOR USE IN THE TREATMENT OF SEPSIS | GENFIT (FR) | 2022-11-17 | — | — | WO | disclosed |