SCHEMBL30007655

SCHEMBL30007655

CN(C)c1ccccc1CSCc1ccccc1N(C)C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.46
CYP1A2 P05177 2/20 0.43
CYP2C9 P11712 2/20 0.43
CYP2C19 P33261 2/20 0.43
AR P10275 1/20 0.39
MAPT P10636 4/20 0.39
ALDH1A1 P00352 3/20 0.39
GAA P10253 2/20 0.39
TSHR P16473 2/20 0.39
TP53 P04637 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
KDM4E B2RXH2 1/20 0.38
CHEK1 O14757 1/20 0.38
NEK2 P51955 1/20 0.38
LIMK1 P53667 1/20 0.38
DYRK1A Q13627 1/20 0.38
CLK4 Q9HAZ1 1/20 0.38
LMNA P02545 2/20 0.37
MAPK1 P28482 2/20 0.37
L3MBTL1 Q9Y468 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10954119 0.85 CYP1A2 (0.56) ACHECYP1A2CYP2C9CYP2C19AR
SCHEMBL22911513 0.84 AR (0.38) ACHEARMAPTALDH1A1GAA
SCHEMBL15850624 0.79 MAPK1 (0.41) ARMAPTALDH1A1GAATSHR
SCHEMBL20738253 0.79 MAPT (0.40) CYP1A2ARMAPTALDH1A1GAA
SCHEMBL3871304 0.78 AR (0.50) CYP1A2CYP2C19ARMAPTALDH1A1
SCHEMBL29408555 0.78 AR (0.50) CYP1A2CYP2C19ARMAPTALDH1A1
SCHEMBL27935035 0.76 MAPT (0.41) CYP1A2CYP2C19ARMAPTALDH1A1
SCHEMBL709848 0.76 MAPT (0.46) CYP1A2CYP2C19ARMAPTALDH1A1
SCHEMBL18240374 0.74 AR (0.44) CYP1A2CYP2C19ARMAPTALDH1A1
SCHEMBL8999373 0.74 MAPT (0.40) CYP1A2CYP2C19ARMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115215774-A Deuteration method of methyl sulfide compound 复旦大学 2022-10-21 CN disclosed