Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 3/20 | 0.39 |
| ▸ | CNR2 | P34972 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PTGFR | P43088 | 5/20 | 0.33 |
| ▸ | CTSA | P10619 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25687409 | 0.95 | CFTR (0.40) | CFTRCNR2MAPTPTGFRGABRA5 | |
| SCHEMBL23958734 | 0.89 | CFTR (0.38) | CFTRCNR2MAPTPTGFRGABRA5 | |
| SCHEMBL25687236 | 0.89 | CFTR (0.38) | CFTRCNR2MAPTPTGFRGABRA5 | |
| SCHEMBL25687248 | 0.89 | CFTR (0.37) | CFTRCNR2MAPTPTGFRCTSA | |
| SCHEMBL25231373 | 0.89 | CFTR (0.37) | CFTRCNR2MAPTPTGFRCTSA | |
| SCHEMBL25687246 | 0.89 | CFTR (0.37) | CFTRCNR2MAPTPTGFRCTSA | |
| SCHEMBL25687253 | 0.87 | CFTR (0.36) | CFTRCNR2MAPTPTGFRCTSA | |
| SCHEMBL25275834 | 0.87 | CFTR (0.36) | CFTRCNR2MAPTPTGFRCTSA | |
| SCHEMBL23958886 | 0.85 | CFTR (0.40) | CFTRCNR2MAPTPTGFRGABRA5 | |
| SCHEMBL30211296 | 0.85 | CFTR (0.40) | CFTRCNR2MAPTPTGFRGABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115461336-A | RSV inhibiting 3-substituted quinoline and cinnoline derivatives | 爱尔兰詹森科学公司 | 2022-12-09 | — | — | CN | disclosed |