SCHEMBL30007758

SCHEMBL30007758

COc1cc(C(=O)O)cc2cc(C(F)(F)F)cnc12

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.44
CA1 P00915 2/20 0.44
CA2 P00918 2/20 0.44
CA4 P22748 2/20 0.44
CA6 P23280 2/20 0.44
CA7 P43166 2/20 0.44
CA9 Q16790 2/20 0.44
CA14 Q9ULX7 2/20 0.44
CA3 P07451 1/20 0.44
PKM P14618 1/20 0.44
CA5A P35218 1/20 0.44
CA5B Q9Y2D0 1/20 0.44
PTGS2 P35354 1/20 0.42
HPGDS O60760 1/20 0.40
MRGPRX4 Q96LA9 3/20 0.40
TPMT P51580 2/20 0.40
ALDH1A1 P00352 1/20 0.40
AGBL2 Q5U5Z8 1/20 0.40
MAPK1 P28482 2/20 0.39
CNR2 P34972 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23195644 1.00 CA12 (0.44) CA12CA1CA2CA4CA6
SCHEMBL23905505 0.88 NOTUM (0.46) HPGDSALDH1A1MAPK1HTTLMNA
SCHEMBL30339881 0.88 SMN1; SMN2 (0.44) HPGDSALDH1A1MAPK1HTTTSHR
SCHEMBL25114964 0.84 MAOB (0.45) ALDH1A1PDGFRBPDGFRARAB9A
SCHEMBL23195634 0.82 CA12 (0.47) CA12CA1CA2CA4CA6
SCHEMBL23195851 0.80 CNR2 (0.49) CA12CA1CA2CA4CA6
SCHEMBL23883072 0.80 CA12 (0.53) CA12CA1CA2CA4CA6
SCHEMBL23883077 0.80 KDM4E (0.49) CA12CA1CA2CA4CA6
SCHEMBL23905724 0.79 CA12 (0.47) CA12CA1CA2CA4CA6
SCHEMBL23195609 0.79 CA12 (0.47) CA12CA1CA2CA4CA6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119173505-A Antiviral heterocyclic compounds 英安塔制药有限公司 2024-12-20 CN disclosed
CN-115461336-A RSV inhibiting 3-substituted quinoline and cinnoline derivatives 爱尔兰詹森科学公司 2022-12-09 CN disclosed