SCHEMBL3000803

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16139053	0.92	CYP3A4 (0.56)	CYP3A4ABCB1ABCC1KCNH2TSHR
	SCHEMBL3009832	0.91	CYP3A4 (0.64)	CYP3A4ABCB1ABCC1KCNH2TSHR
	SCHEMBL3017264	0.88	CYP3A4 (0.61)	CYP3A4ABCB1ABCC1KCNH2TSHR
	SCHEMBL16138736	0.86	CYP3A4 (0.49)	CYP3A4ABCB1ABCC1KCNH2TSHR
	SCHEMBL19261410	0.86	CYP3A4 (0.49)	CYP3A4ABCB1ABCC1KCNH2TSHR
	SCHEMBL3000903	0.85	CYP3A4 (0.59)	CYP3A4ABCB1ABCC1KCNH2TSHR
	SCHEMBL3001174	0.83	CYP3A4 (0.57)	CYP3A4ABCB1ABCC1KCNH2TSHR
	SCHEMBL16138845	0.83	ABCB1 (0.55)	CYP3A4ABCB1ABCC1KCNH2TSHR
	SCHEMBL3014637	0.83	CYP3A4 (0.55)	CYP3A4ABCB1ABCC1KCNH2TSHR
	SCHEMBL3010889	0.83	CYP3A4 (0.57)	CYP3A4ABCB1ABCC1KCNH2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.