Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 9/20 | 0.45 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30007672 | 0.82 | PAK1 (0.53) | KMT2AMEN1LMNAHPGDCA1 | |
| Hydrochloric Acid SCHEMBL30007950 | 0.77 | ATR (0.41) | — | |
| SCHEMBL30007878 | 0.74 | NAMPT (0.48) | KMT2AMEN1LMNACA1CA2 | |
| SCHEMBL30007741 | 0.72 | CA12 (0.44) | KDM4CCA1CA2CA7CA9 | |
| SCHEMBL30008315 | 0.71 | HRH4 (0.49) | KMT2ANPC1RAB9ALMNA | |
| SCHEMBL13302250 | 0.68 | KMT2A (0.76) | KMT2ARXFP1MEN1NPC1RAB9A | |
| SCHEMBL30007739 | 0.67 | NAMPT (0.43) | — | |
| SCHEMBL26100539 | 0.66 | HRH4 (0.68) | KMT2ARXFP1MEN1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL30008041 | 0.66 | CDK5 (0.44) | — | |
| SCHEMBL14575797 | 0.65 | PIK3CA (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022237922-A1 | ANTITUMOR COMPOUNDS BASED ON NITROGEN HETEROCYCLES AND USE THEREOF AS MEDICAMENTS | FAKULTNI NEMOCNICE HRADEC KRALOVE (CZ) | 2022-11-17 | — | — | WO | disclosed |