Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 3/20 | 0.55 |
| ▸ | JAK2 | O60674 | 4/20 | 0.54 |
| ▸ | TTBK1 | Q5TCY1 | 3/20 | 0.53 |
| ▸ | TTBK2 | Q6IQ55 | 3/20 | 0.53 |
| ▸ | JAK1 | P23458 | 1/20 | 0.52 |
| ▸ | FLT3 | P36888 | 3/20 | 0.51 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.51 |
| ▸ | KIT | P10721 | 1/20 | 0.51 |
| ▸ | MAP3K19 | Q56UN5 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | IKBKB | O14920 | 1/20 | 0.50 |
| ▸ | CHUK | O15111 | 1/20 | 0.50 |
| ▸ | JAK3 | P52333 | 3/20 | 0.48 |
| ▸ | GSK3B | P49841 | 3/20 | 0.48 |
| ▸ | AURKA | O14965 | 2/20 | 0.48 |
| ▸ | DAPK3 | O43293 | 2/20 | 0.48 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30009157 | 0.87 | BTK (0.55) | BTKJAK2TTBK1TTBK2FLT3 | |
| SCHEMBL15661177 | 0.86 | JAK2 (0.70) | BTKJAK2TTBK1TTBK2JAK1 | |
| SCHEMBL20752269 | 0.80 | JAK2 (0.60) | BTKJAK2JAK1FLT3PDGFRB | |
| SCHEMBL30008724 | 0.78 | JAK2 (0.52) | BTKJAK2FLT3PDGFRBIKBKB | |
| SCHEMBL16793627 | 0.78 | JAK2 (0.66) | BTKJAK2JAK1FLT3PDGFRB | |
| SCHEMBL30009483 | 0.77 | KIT (0.67) | JAK1KITIKBKBCHUKAURKB | |
| SCHEMBL24805255 | 0.75 | IKBKB (0.65) | BTKJAK2JAK1FLT3PDGFRB | |
| SCHEMBL30009347 | 0.75 | JAK2 (0.55) | BTKJAK2JAK1FLT3PDGFRB | |
| SCHEMBL15660156 | 0.75 | BTK (0.57) | BTKJAK2TTBK1TTBK2JAK1 | |
| SCHEMBL21044826 | 0.74 | JAK2 (0.60) | BTKJAK2JAK1FLT3PDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11524968-B2 | Heterocyclic compound as a protein kinase inhibitor | HK INNO.N CORPORATION (KR) | 2022-12-13 | — | — | US | claimed |
| US-11524968-B2 | Heterocyclic compound as a protein kinase inhibitor | HK INNO.N CORPORATION (KR) | 2022-12-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11524968-B2 | Heterocyclic compound as a protein kinase inhibitor | MAP3K20, MAP3K15, MAP3K1 | BTK 236/4885JAK2 61/4885TTBK1 257/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.