SCHEMBL30008736

SCHEMBL30008736

CCc1cc(-c2ccnc3[nH]ccc23)ccc1NS(=O)(=O)C1CC1

nearest known ligand 0.53

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
IKBKB O14920 9/20 0.53
CHUK O15111 8/20 0.53
PIK3C3 Q8NEB9 1/20 0.52
JAK1 P23458 2/20 0.49
PRKCI P41743 1/20 0.46
NEK1 Q96PY6 5/20 0.45
NUDT1 P36639 1/20 0.45
CCNK O75909 1/20 0.44
CDK12 Q9NYV4 1/20 0.44
CIT O14578 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30009578 0.96 PIK3C3 (0.55) IKBKBCHUKPIK3C3JAK1PRKCI
SCHEMBL30009803 0.86 IKBKB (0.55) IKBKBCHUKJAK1PRKCINEK1
SCHEMBL30010083 0.85 PIK3C3 (0.54) IKBKBCHUKPIK3C3JAK1PRKCI
SCHEMBL30009338 0.84 JAK1 (0.54) IKBKBCHUKJAK1PRKCINEK1
SCHEMBL30009353 0.82 JAK1 (0.61) IKBKBCHUKJAK1PRKCINEK1
SCHEMBL30009401 0.81 PIK3C3 (0.57) IKBKBCHUKPIK3C3JAK1PRKCI
SCHEMBL30009836 0.80 PIK3C3 (0.59) IKBKBCHUKPIK3C3JAK1PRKCI
SCHEMBL30009209 0.80 JAK1 (0.59) IKBKBCHUKPIK3C3JAK1CCNK
SCHEMBL30008725 0.80 IKBKB (0.69) IKBKBCHUKPIK3C3JAK1NEK1
SCHEMBL20917882 0.79 JAK1 (0.78) JAK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11524968-B2 Heterocyclic compound as a protein kinase inhibitor HK INNO.N CORPORATION (KR) 2022-12-13 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11524968-B2 Heterocyclic compound as a protein kinase inhibitor MAP3K20, MAP3K15, MAP3K1 IKBKB 294/4885CHUK 53/4885PIK3C3 288/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.