Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CIT | O14578 | 10/20 | 0.61 |
| ▸ | IKBKB | O14920 | 5/20 | 0.53 |
| ▸ | CHUK | O15111 | 4/20 | 0.53 |
| ▸ | JAK1 | P23458 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30008979 | 0.93 | CIT (0.59) | CITIKBKBCHUKJAK1 | |
| SCHEMBL30009497 | 0.91 | JAK1 (0.61) | CITIKBKBCHUKJAK1 | |
| SCHEMBL30008811 | 0.88 | CIT (0.60) | CITIKBKBCHUKJAK1 | |
| SCHEMBL30009619 | 0.87 | CIT (0.56) | CITIKBKBCHUKJAK1 | |
| SCHEMBL30008938 | 0.87 | CIT (0.60) | CITIKBKBCHUKJAK1 | |
| SCHEMBL30009209 | 0.85 | JAK1 (0.59) | CITIKBKBCHUKJAK1 | |
| SCHEMBL30009247 | 0.84 | CIT (0.62) | CITIKBKBCHUKJAK1 | |
| SCHEMBL30009495 | 0.84 | JAK1 (0.62) | CITIKBKBCHUKJAK1 | |
| SCHEMBL30009525 | 0.83 | IKBKB (0.76) | CITIKBKBCHUK | |
| SCHEMBL30009873 | 0.81 | JAK1 (0.60) | CITIKBKBCHUKJAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11524968-B2 | Heterocyclic compound as a protein kinase inhibitor | HK INNO.N CORPORATION (KR) | 2022-12-13 | — | — | US | claimed |
| US-11524968-B2 | Heterocyclic compound as a protein kinase inhibitor | HK INNO.N CORPORATION (KR) | 2022-12-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11524968-B2 | Heterocyclic compound as a protein kinase inhibitor | MAP3K20, MAP3K15, MAP3K1 | CIT 417/4885IKBKB 294/4885CHUK 53/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.