SCHEMBL30009155

SCHEMBL30009155

N#CCCCS(=O)(=O)Nc1ccc(-c2ccnc3[nH]ccc23)cc1

nearest known ligand 0.63

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
IKBKB O14920 6/20 0.63
CHUK O15111 5/20 0.63
CIT O14578 12/20 0.54
JAK1 P23458 1/20 0.52
NEK1 Q96PY6 1/20 0.51
ROCK1 Q13464 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30009376 0.86 IKBKB (0.70) IKBKBCHUKCITNEK1ROCK1
SCHEMBL30009167 0.86 IKBKB (0.66) IKBKBCHUKCITJAK1NEK1
SCHEMBL30008749 0.83 IKBKB (0.69) IKBKBCHUKCITJAK1NEK1
SCHEMBL30010048 0.83 IKBKB (0.73) IKBKBCHUKCITNEK1ROCK1
SCHEMBL30009525 0.83 IKBKB (0.76) IKBKBCHUKCITNEK1ROCK1
SCHEMBL30009619 0.83 CIT (0.56) IKBKBCHUKCITJAK1
SCHEMBL30009375 0.83 JAK1 (0.56) IKBKBCHUKCITJAK1NEK1
SCHEMBL30009881 0.83 IKBKB (0.68) IKBKBCHUKCIT
SCHEMBL30008721 0.82 IKBKB (0.70) IKBKBCHUKCITJAK1NEK1
SCHEMBL30009222 0.81 IKBKB (0.70) IKBKBCHUKCIT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11524968-B2 Heterocyclic compound as a protein kinase inhibitor HK INNO.N CORPORATION (KR) 2022-12-13 US claimed
US-11524968-B2 Heterocyclic compound as a protein kinase inhibitor HK INNO.N CORPORATION (KR) 2022-12-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11524968-B2 Heterocyclic compound as a protein kinase inhibitor MAP3K20, MAP3K15, MAP3K1 IKBKB 294/4885CHUK 53/4885CIT 417/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.