Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK1 | P23458 | 13/20 | 0.52 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.47 |
| ▸ | CDK9 | P50750 | 2/20 | 0.47 |
| ▸ | JAK3 | P52333 | 10/20 | 0.46 |
| ▸ | JAK2 | O60674 | 8/20 | 0.46 |
| ▸ | TYK2 | P29597 | 2/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14493885 | 0.89 | JAK1 (0.57) | JAK1CCNT1CDK9JAK3JAK2 | |
| SCHEMBL12696510 | 0.87 | JAK1 (0.49) | JAK1CCNT1CDK9JAK3JAK2 | |
| SCHEMBL12613120 | 0.81 | JAK1 (0.47) | JAK1JAK3JAK2TYK2 | |
| SCHEMBL12612582 | 0.81 | JAK1 (0.47) | JAK1JAK3JAK2TYK2 | |
| SCHEMBL30009431 | 0.81 | JAK1 (0.55) | JAK1JAK3JAK2TYK2 | |
| SCHEMBL29931152 | 0.81 | JAK1 (0.67) | JAK1JAK3JAK2TYK2 | |
| SCHEMBL12613663 | 0.80 | JAK1 (0.48) | JAK1JAK3JAK2TYK2 | |
| SCHEMBL30009330 | 0.79 | JAK1 (0.51) | JAK1JAK3JAK2 | |
| SCHEMBL20919095 | 0.78 | JAK1 (0.84) | JAK1 | |
| SCHEMBL12612169 | 0.78 | JAK1 (0.56) | JAK1JAK3JAK2TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11524968-B2 | Heterocyclic compound as a protein kinase inhibitor | HK INNO.N CORPORATION (KR) | 2022-12-13 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11524968-B2 | Heterocyclic compound as a protein kinase inhibitor | MAP3K20, MAP3K15, MAP3K1 | JAK1 83/4885CCNT1 2852/4885CDK9 330/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.