Sugi Predict

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SCHEMBL30009385

SCHEMBL30009385

CC(C)(C)NC(=O)c1cnn2ccc(N3C[C@H](O)C[C@@H]3c3cccc(F)c3)nc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ JAK2 O60674 20/20 1.00
▸ NTRK1 P04629 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL944521 1.00 JAK2 (1.00) JAK2NTRK1
SCHEMBL2694113 0.91 NTRK1 (1.00) JAK2NTRK1
SCHEMBL2694429 0.91 NTRK1 (1.00) JAK2NTRK1
SCHEMBL2692464 0.88 JAK2 (1.00) JAK2NTRK1
SCHEMBL932751 0.88 NTRK1 (0.82) JAK2NTRK1
SCHEMBL933270 0.88 NTRK1 (0.82) JAK2NTRK1
SCHEMBL2694809 0.87 NTRK1 (1.00) JAK2NTRK1
SCHEMBL30009555 0.87 NTRK1 (1.00) JAK2NTRK1
SCHEMBL2695142 0.87 NTRK1 (1.00) JAK2NTRK1
SCHEMBL2695147 0.87 NTRK1 (1.00) JAK2NTRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4041259-A1 FEEDER-BASED AND FEEDER-FREE STEM CELL CULTURE SYSTEMS FOR STRATIFIED EPITHELIAL STEM CELLS, AND USES RELATED THERETO University of Houston System (US) 2022-08-17 — — EP disclosed