Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 17/20 | 1.00 |
| ▸ | JAK1 | P23458 | 1/20 | 0.60 |
| ▸ | JAK3 | P52333 | 1/20 | 0.60 |
| ▸ | AURKA | O14965 | 3/20 | 0.54 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.54 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.54 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL656578 | 1.00 | SYK (1.00) | SYKJAK1JAK3AURKAMAPK8 | |
| SCHEMBL30009889 | 1.00 | SYK (1.00) | SYKJAK1JAK3AURKAMAPK8 | |
| SCHEMBL656760 | 1.00 | SYK (1.00) | SYKJAK1JAK3AURKAMAPK8 | |
| SCHEMBL657850 | 0.93 | SYK (0.86) | SYKJAK1JAK3AURKAMAPK8 | |
| SCHEMBL656397 | 0.93 | SYK (0.86) | SYKJAK1JAK3AURKAMAPK8 | |
| SCHEMBL656700 | 0.90 | SYK (0.81) | SYKAURKAMAPK8AURKBCDK19 | |
| SCHEMBL657167 | 0.86 | SYK (0.75) | SYKJAK1JAK3 | |
| SCHEMBL13007743 | 0.84 | SYK (0.72) | SYKJAK1JAK3AURKAMAPK8 | |
| SCHEMBL12854318 | 0.84 | SYK (0.72) | SYKJAK1JAK3 | |
| SCHEMBL2745738 | 0.84 | SYK (0.72) | SYKJAK1JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4041259-A1 | FEEDER-BASED AND FEEDER-FREE STEM CELL CULTURE SYSTEMS FOR STRATIFIED EPITHELIAL STEM CELLS, AND USES RELATED THERETO | University of Houston System (US) | 2022-08-17 | — | — | EP | disclosed |