Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKB | Q96GD4 | 2/20 | 0.62 |
| ▸ | AURKA | O14965 | 1/20 | 0.62 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.62 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.62 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.54 |
| ▸ | JAK2 | O60674 | 17/20 | 0.53 |
| ▸ | JAK1 | P23458 | 12/20 | 0.53 |
| ▸ | JAK3 | P52333 | 7/20 | 0.52 |
| ▸ | TYK2 | P29597 | 3/20 | 0.52 |
| ▸ | STAT3 | P40763 | 1/20 | 0.48 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.47 |
| ▸ | IKBKB | O14920 | 1/20 | 0.47 |
| ▸ | CHUK | O15111 | 1/20 | 0.47 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.47 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.47 |
| ▸ | PAK4 | O96013 | 1/20 | 0.47 |
| ▸ | CSF1R | P07333 | 1/20 | 0.47 |
| ▸ | RET | P07949 | 1/20 | 0.47 |
| ▸ | IGF1R | P08069 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL99373 | 1.00 | AURKB (0.62) | AURKBAURKAINCENPTPX2GRM4 | |
| SCHEMBL100283 | 0.93 | AURKB (0.59) | AURKBAURKAINCENPTPX2GRM4 | |
| SCHEMBL100379 | 0.91 | AURKA (0.57) | AURKBAURKAINCENPTPX2GRM4 | |
| Trifluoroacetic Acid SCHEMBL99804 | 0.90 | AURKA (0.51) | AURKBAURKAINCENPTPX2GRM4 | |
| SCHEMBL23543160 | 0.84 | AURKB (0.66) | AURKBAURKAINCENPTPX2GRM4 | |
| SCHEMBL20879725 | 0.84 | AURKB (0.70) | AURKBAURKAINCENPTPX2GRM4 | |
| SCHEMBL100071 | 0.82 | AURKB (0.63) | AURKBAURKAINCENPTPX2GRM4 | |
| SCHEMBL28338366 | 0.81 | AURKB (0.65) | AURKBAURKAINCENPTPX2GRM4 | |
| SCHEMBL101593 | 0.81 | JAK2 (0.62) | AURKBAURKAJAK2JAK1JAK3 | |
| SCHEMBL14052556 | 0.81 | AURKB (0.65) | AURKBAURKAINCENPTPX2GRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11524968-B2 | Heterocyclic compound as a protein kinase inhibitor | HK INNO.N CORPORATION (KR) | 2022-12-13 | — | — | US | claimed |
| US-11524968-B2 | Heterocyclic compound as a protein kinase inhibitor | HK INNO.N CORPORATION (KR) | 2022-12-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11524968-B2 | Heterocyclic compound as a protein kinase inhibitor | MAP3K20, MAP3K15, MAP3K1 | AURKB 643/4885AURKA 422/4885INCENP 4533/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.