SCHEMBL30009447

SCHEMBL30009447

CC(C)C[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](N)CC(N)=O)C(=O)N[C@@H](CCC(=O)O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(=N)N)C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
NMUR2 Q9GZQ4 5/20 0.52
NMUR1 Q9HB89 5/20 0.52
MAPK8 P45983 1/20 0.52
MAPK9 P45984 1/20 0.52
MAPK10 P53779 1/20 0.52
RAMP3 O60896 7/20 0.51
CALCR P30988 7/20 0.51
OPRM1 P35372 2/20 0.49
OPRK1 P41145 2/20 0.49
NPY2R P49146 3/20 0.49
NPY4R P50391 3/20 0.49
NPY5R Q15761 3/20 0.49
NPY1R P25929 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30009114 0.94 NPY2R (0.54) MAPK8MAPK9MAPK10RAMP3CALCR
SCHEMBL31416061 0.93 RAMP3 (0.51) NMUR2NMUR1MAPK8MAPK9MAPK10
SCHEMBL29437932 0.93 RAMP3 (0.50) NMUR2NMUR1MAPK8MAPK9MAPK10
SCHEMBL29437941 0.92 RAMP3 (0.49) NMUR2NMUR1MAPK8MAPK9MAPK10
SCHEMBL29453625 0.92 RAMP3 (0.53) NMUR2NMUR1RAMP3CALCRNPY2R
SCHEMBL31416058 0.91 RAMP3 (0.52) MAPK8MAPK9MAPK10RAMP3CALCR
SCHEMBL30401141 0.91 NMUR2 (0.53) NMUR2NMUR1RAMP3CALCRNPY2R
SCHEMBL29437933 0.91 RAMP3 (0.49) NMUR2NMUR1MAPK8MAPK9MAPK10
SCHEMBL29679504 0.91 RAMP3 (0.57) MAPK8MAPK9MAPK10RAMP3CALCR
SCHEMBL31344127 0.91 NMUR2 (0.47) NMUR2NMUR1MAPK8MAPK9MAPK10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115353551-B Oat-derived GLP-1 secretion-promoting oligopeptide and preparation method and application thereof 上海理工大学 2024-01-26 CN claimed
CN-115353551-A Oat-derived GLP-1 secretion promoting oligopeptide and preparation method and application thereof 上海理工大学 2022-11-18 CN claimed
CN-115353551-B Oat-derived GLP-1 secretion-promoting oligopeptide and preparation method and application thereof 上海理工大学 2024-01-26 CN disclosed
CN-115353551-B Oat-derived GLP-1 secretion-promoting oligopeptide and preparation method and application thereof 上海理工大学 2024-01-26 CN disclosed
CN-115353551-A Oat-derived GLP-1 secretion promoting oligopeptide and preparation method and application thereof 上海理工大学 2022-11-18 CN disclosed
CN-115353551-A Oat-derived GLP-1 secretion promoting oligopeptide and preparation method and application thereof 上海理工大学 2022-11-18 CN disclosed