Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK1 | P23458 | 4/20 | 0.60 |
| ▸ | IKBKB | O14920 | 1/20 | 0.53 |
| ▸ | CHUK | O15111 | 1/20 | 0.53 |
| ▸ | KIT | P10721 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | JAK3 | P52333 | 3/20 | 0.48 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.47 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.47 |
| ▸ | JAK2 | O60674 | 5/20 | 0.47 |
| ▸ | TYK2 | P29597 | 1/20 | 0.45 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.45 |
| ▸ | AURKA | O14965 | 1/20 | 0.45 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.45 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.45 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.45 |
| ▸ | PAK4 | O96013 | 1/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.45 |
| ▸ | LCK | P06239 | 1/20 | 0.45 |
| ▸ | CSF1R | P07333 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30009314 | 0.82 | IKBKB (0.62) | JAK1IKBKBCHUKPOLBJAK3 | |
| SCHEMBL30008775 | 0.82 | POLB (0.50) | JAK1KITPOLBMAP4K4ABL1 | |
| SCHEMBL24805256 | 0.78 | IKBKB (0.70) | IKBKBCHUKKITJAK3JAK2 | |
| SCHEMBL20918706 | 0.76 | JAK1 (1.00) | JAK1 | |
| SCHEMBL30009248 | 0.75 | IKBKB (0.61) | JAK1IKBKBCHUKKITJAK3 | |
| SCHEMBL19823110 | 0.74 | CSF1R (0.55) | JAK1IKBKBCHUKKITJAK3 | |
| SCHEMBL30009334 | 0.74 | IKBKB (0.60) | JAK1IKBKBCHUKKITJAK3 | |
| SCHEMBL30009538 | 0.73 | KIT (0.69) | JAK1IKBKBCHUKKITJAK3 | |
| SCHEMBL30008799 | 0.73 | KIT (0.55) | JAK1IKBKBCHUKKITJAK3 | |
| SCHEMBL30009885 | 0.71 | IKBKB (0.71) | JAK1IKBKBCHUKJAK3JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11524968-B2 | Heterocyclic compound as a protein kinase inhibitor | HK INNO.N CORPORATION (KR) | 2022-12-13 | — | — | US | claimed |
| US-11524968-B2 | Heterocyclic compound as a protein kinase inhibitor | HK INNO.N CORPORATION (KR) | 2022-12-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11524968-B2 | Heterocyclic compound as a protein kinase inhibitor | MAP3K20, MAP3K15, MAP3K1 | JAK1 83/4885IKBKB 294/4885CHUK 53/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.