Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CIT | O14578 | 17/20 | 0.64 |
| ▸ | JAK1 | P23458 | 1/20 | 0.60 |
| ▸ | AURKA | O14965 | 1/20 | 0.59 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.59 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30008944 | 0.89 | JAK1 (0.62) | CITJAK1AURKAAURKB | |
| SCHEMBL4312212 | 0.88 | CIT (0.52) | CITJAK1AURKAAURKB | |
| SCHEMBL30009331 | 0.85 | CIT (0.58) | CITJAK1AURKB | |
| SCHEMBL30009201 | 0.85 | JAK1 (0.62) | CITJAK1AURKAAURKB | |
| SCHEMBL4316670 | 0.84 | AURKB (0.54) | CITJAK1AURKAAURKB | |
| SCHEMBL4794287 | 0.84 | CIT (0.66) | CITAURKAAURKBROCK2 | |
| SCHEMBL4307065 | 0.84 | AURKB (0.83) | AURKAAURKB | |
| SCHEMBL4316896 | 0.84 | AURKB (0.53) | CITJAK1AURKAAURKB | |
| SCHEMBL4794268 | 0.84 | AURKB (0.73) | CITAURKAAURKBROCK2 | |
| SCHEMBL1718374 | 0.83 | CIT (0.71) | CIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11524968-B2 | Heterocyclic compound as a protein kinase inhibitor | HK INNO.N CORPORATION (KR) | 2022-12-13 | — | — | US | claimed |
| US-11524968-B2 | Heterocyclic compound as a protein kinase inhibitor | HK INNO.N CORPORATION (KR) | 2022-12-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11524968-B2 | Heterocyclic compound as a protein kinase inhibitor | MAP3K20, MAP3K15, MAP3K1 | CIT 417/4885JAK1 83/4885AURKA 422/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.