Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 1/20 | 0.65 |
| ▸ | CCNK | O75909 | 4/20 | 0.64 |
| ▸ | CDK12 | Q9NYV4 | 4/20 | 0.64 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.60 |
| ▸ | AURKA | O14965 | 2/20 | 0.60 |
| ▸ | INCENP | Q9NQS7 | 2/20 | 0.60 |
| ▸ | TPX2 | Q9ULW0 | 2/20 | 0.60 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.58 |
| ▸ | IKBKB | O14920 | 1/20 | 0.58 |
| ▸ | CHUK | O15111 | 1/20 | 0.58 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.58 |
| ▸ | JAK2 | O60674 | 1/20 | 0.58 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.58 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.58 |
| ▸ | PAK4 | O96013 | 1/20 | 0.58 |
| ▸ | CSF1R | P07333 | 1/20 | 0.58 |
| ▸ | RET | P07949 | 1/20 | 0.58 |
| ▸ | IGF1R | P08069 | 1/20 | 0.58 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.58 |
| ▸ | PRKACA | P17612 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL99234 | 1.00 | GRM4 (0.65) | GRM4CCNKCDK12AURKBAURKA | |
| Trifluoroacetic Acid SCHEMBL4082781 | 0.91 | JAK1 (0.55) | GRM4CCNKCDK12AURKBAURKA | |
| SCHEMBL29541183 | 0.91 | CCNK (0.67) | GRM4CCNKCDK12AURKBAURKA | |
| SCHEMBL99693 | 0.91 | CCNK (0.67) | GRM4CCNKCDK12AURKBAURKA | |
| SCHEMBL100073 | 0.87 | GRM4 (0.55) | GRM4CCNKCDK12AURKBAURKA | |
| SCHEMBL16673732 | 0.86 | GRM4 (0.60) | GRM4CCNKCDK12AURKBAURKA | |
| SCHEMBL101771 | 0.85 | AURKB (0.54) | GRM4CCNKCDK12AURKBAURKA | |
| SCHEMBL99686 | 0.85 | AURKB (0.56) | GRM4CCNKCDK12AURKBAURKA | |
| SCHEMBL29540389 | 0.85 | AURKB (0.56) | GRM4CCNKCDK12AURKBAURKA | |
| SCHEMBL99272 | 0.85 | GRM4 (0.58) | GRM4CCNKCDK12AURKBAURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11524968-B2 | Heterocyclic compound as a protein kinase inhibitor | HK INNO.N CORPORATION (KR) | 2022-12-13 | — | — | US | claimed |
| US-11524968-B2 | Heterocyclic compound as a protein kinase inhibitor | HK INNO.N CORPORATION (KR) | 2022-12-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11524968-B2 | Heterocyclic compound as a protein kinase inhibitor | MAP3K20, MAP3K15, MAP3K1 | GRM4 1716/4885CCNK 820/4885CDK12 525/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.