Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 20/20 | 0.53 |
| ▸ | SRPK2 | P78362 | 1/20 | 0.47 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.47 |
| ▸ | EML4 | Q9HC35 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27087519 | 0.89 | ALK (0.59) | ALKSRPK2SRPK1EML4 | |
| SCHEMBL29940684 | 0.89 | ALK (0.59) | ALKSRPK2SRPK1EML4 | |
| SCHEMBL27087618 | 0.89 | ALK (0.64) | ALKSRPK2SRPK1EML4 | |
| SCHEMBL30760746 | 0.89 | ALK (0.63) | ALKSRPK2SRPK1EML4 | |
| SCHEMBL27087635 | 0.87 | ALK (0.55) | ALKSRPK2SRPK1EML4 | |
| SCHEMBL30009163 | 0.87 | ALK (0.60) | ALKSRPK2SRPK1EML4 | |
| SCHEMBL28913325 | 0.86 | ALK (0.59) | ALKEML4 | |
| SCHEMBL27087580 | 0.86 | ALK (0.64) | ALK | |
| SCHEMBL27087609 | 0.83 | ALK (0.62) | ALKEML4 | |
| SCHEMBL27087598 | 0.83 | ALK (0.55) | ALKSRPK2SRPK1EML4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022237813-A1 | COMPOUND HAVING ALK INHIBITORY ACTIVITY, PREPARATION METHOD THEREFOR AND USE THEREOF | 盛世泰科生物医药技术(苏州)有限公司 | 2022-11-17 | — | — | WO | disclosed |