SCHEMBL30009748

SCHEMBL30009748

O=C(CCl)NCc1cccc2c1C(=O)N(C1CCC(=O)NC1=O)C2=O

nearest known ligand 0.80

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
DDB1 Q16531 19/20 0.80
CRBN Q96SW2 19/20 0.80
IKZF3 Q9UKT9 2/20 0.59
TNF P01375 1/20 0.59
IL1B P01584 1/20 0.59
TBXA2R P21731 1/20 0.59
IKZF1 Q13422 1/20 0.59
ALDH1A1 P00352 1/20 0.56
CHRM2 P08172 1/20 0.56
OPRM1 P35372 1/20 0.56
CYP1A2 P05177 1/20 0.56
TSHR P16473 1/20 0.56
TDP1 Q9NUW8 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL476904 1.00 DDB1 (0.80) DDB1CRBNIKZF3TNFIL1B
SCHEMBL476960 0.91 DDB1 (0.81) DDB1CRBNIKZF3TNFIL1B
SCHEMBL30041341 0.91 DDB1 (0.81) DDB1CRBNIKZF3TNFIL1B
SCHEMBL2382971 0.91 DDB1 (0.78) DDB1CRBNIKZF3TNFIL1B
Hydrochloric Acid SCHEMBL2381756 0.90 DDB1 (0.77) DDB1CRBNIKZF3TNFIL1B
SCHEMBL2384835 0.90 DDB1 (0.77) DDB1CRBNIKZF3TNFIL1B
SCHEMBL5136914 0.90 DDB1 (0.83) DDB1CRBNIKZF3TNFIL1B
SCHEMBL20118479 0.89 DDB1 (0.79) DDB1CRBNIKZF3TNFIL1B
SCHEMBL5549995 0.89 DDB1 (0.75) DDB1CRBNIKZF3TNFIL1B
SCHEMBL2382251 0.89 DDB1 (0.75) DDB1CRBNIKZF3TNFIL1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260125449-A1 ARTICLES OF MANUFACTURE AND METHODS FOR TREATMENT USING ADOPTIVE CELL THERAPY JUNO THERAPEUTICS, INC. (US) 2026-05-07 US disclosed
US-12583904-B2 Articles of manufacture and methods for treatment using adoptive cell therapy JUNO THERAPEUTICS, INC. (US) 2026-03-24 US disclosed
EP-4611798-A1 METHODS OF TREATMENT WITH T CELL THERAPY AND IMMUNOMODULATORY AGENT MAINTENANCE THERAPY CELGENE CORPORATION (US) 2025-09-10 EP disclosed
EP-4543923-A1 TREATMENT METHODS FOR SECOND LINE THERAPY OF CD19-TARGETED CAR T CELLS Juno Therapeutics, Inc. (US) 2025-04-30 EP disclosed
US-20250011387-A1 ARTICLES OF MANUFACTURE AND METHODS FOR TREATMENT USING ADOPTIVE CELL THERAPY JUNO THERAPEUTICS, INC. (US) 2025-01-09 US disclosed
CN-118662614-A Articles and methods of treatment using adoptive cell therapy 朱诺治疗学股份有限公司 2024-09-20 CN disclosed
WO-2024097905-A1 METHODS OF TREATMENT WITH T CELL THERAPY AND IMMUNOMODULATORY AGENT MAINTENANCE THERAPY CELGENE CORPORATION (US) 2024-05-10 WO disclosed
EP-3886875-B1 METHODS FOR TREATMENT USING ADOPTIVE CELL THERAPY JUNO THERAPEUTICS INC (US) 2024-05-08 EP disclosed
CN-111225675-B Articles and methods of treatment using adoptive cell therapy 朱诺治疗学股份有限公司 2024-05-03 CN disclosed
WO-2023250400-A1 TREATMENT METHODS FOR SECOND LINE THERAPY OF CD19-TARGETED CAR T CELLS JUNO THERAPEUTICS, INC. (US) 2023-12-28 WO disclosed
CN-115282165-A Natural killer cells from placenta 细胞结构公司 2022-11-04 CN disclosed
CN-115137753-A Natural killer cells from placenta 细胞结构公司 2022-10-04 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250011387-A1 ARTICLES OF MANUFACTURE AND METHODS FOR TREATMENT USING ADOPTIVE CELL THERAPY ICOS, PBK, BCL6 DDB1 3053/4885CRBN 222/4885IKZF3 65/4885
US-12583904-B2 Articles of manufacture and methods for treatment using adoptive cell therapy CD4, CD2, ICOS DDB1 4105/4885CRBN 758/4885IKZF3 131/4885
US-20260125449-A1 ARTICLES OF MANUFACTURE AND METHODS FOR TREATMENT USING ADOPTIVE CELL THERAPY MALT1, BCL9, ICOS DDB1 4720/4885CRBN 134/4885IKZF3 448/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.