Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 11/20 | 0.80 |
| ▸ | PDE4D | Q08499 | 11/20 | 0.80 |
| ▸ | PDE4A | P27815 | 11/20 | 0.80 |
| ▸ | PDE4C | Q08493 | 10/20 | 0.80 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.66 |
| ▸ | CA12 | O43570 | 1/20 | 0.65 |
| ▸ | CA1 | P00915 | 1/20 | 0.65 |
| ▸ | CA2 | P00918 | 1/20 | 0.65 |
| ▸ | CA4 | P22748 | 1/20 | 0.65 |
| ▸ | CA6 | P23280 | 1/20 | 0.65 |
| ▸ | CA7 | P43166 | 1/20 | 0.65 |
| ▸ | TPMT | P51580 | 1/20 | 0.65 |
| ▸ | CA9 | Q16790 | 1/20 | 0.65 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1028427 | 1.00 | PDE4B (0.80) | PDE4BPDE4DPDE4APDE4CMAPK14 | |
| Hydrochloric Acid SCHEMBL6586041 | 0.98 | PDE4B (0.78) | PDE4BPDE4DPDE4APDE4CMAPK14 | |
| SCHEMBL9005494 | 0.98 | PDE4D (0.78) | PDE4BPDE4DPDE4APDE4CMAPK14 | |
| SCHEMBL7336609 | 0.98 | PDE4D (0.78) | PDE4BPDE4DPDE4APDE4CMAPK14 | |
| SCHEMBL6799815 | 0.94 | PDE4B (0.71) | PDE4BPDE4DPDE4APDE4CMAPK14 | |
| SCHEMBL28846183 | 0.94 | PDE4B (0.70) | PDE4BPDE4DPDE4APDE4CMAPK14 | |
| SCHEMBL16544966 | 0.91 | PDE4B (0.67) | PDE4BPDE4DPDE4APDE4CMAPK14 | |
| SCHEMBL27472680 | 0.89 | PDE4D (0.68) | PDE4BPDE4DPDE4APDE4CMAPK14 | |
| SCHEMBL7444846 | 0.89 | PDE4A (1.00) | PDE4BPDE4DPDE4APDE4CMAPK14 | |
| SCHEMBL128167 | 0.88 | PDE4B (0.70) | PDE4BPDE4DPDE4APDE4CMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022237798-A1 | BENZOYLGUANIDINE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 青岛海洋生物医药研究院 | 2022-11-17 | — | — | WO | disclosed |