Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 20/20 | 1.00 |
| ▸ | JAK2 | O60674 | 19/20 | 1.00 |
| ▸ | JAK1 | P23458 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1082852 | 1.00 | NTRK1 (1.00) | NTRK1JAK2JAK1 | |
| SCHEMBL1082853 | 1.00 | NTRK1 (1.00) | NTRK1JAK2JAK1 | |
| SCHEMBL2694236 | 0.92 | NTRK1 (0.85) | NTRK1JAK2 | |
| SCHEMBL2694238 | 0.92 | NTRK1 (0.85) | NTRK1JAK2 | |
| SCHEMBL29794676 | 0.91 | NTRK1 (0.84) | NTRK1JAK2JAK1 | |
| SCHEMBL1024691 | 0.91 | NTRK1 (0.84) | NTRK1JAK2JAK1 | |
| SCHEMBL1024689 | 0.91 | NTRK1 (0.84) | NTRK1JAK2JAK1 | |
| SCHEMBL950406 | 0.91 | NTRK1 (0.88) | NTRK1JAK2 | |
| SCHEMBL950408 | 0.91 | NTRK1 (0.88) | NTRK1JAK2 | |
| SCHEMBL12944299 | 0.90 | NTRK1 (0.88) | NTRK1JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4041259-A1 | FEEDER-BASED AND FEEDER-FREE STEM CELL CULTURE SYSTEMS FOR STRATIFIED EPITHELIAL STEM CELLS, AND USES RELATED THERETO | University of Houston System (US) | 2022-08-17 | — | — | EP | disclosed |