Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 13/20 | 0.66 |
| ▸ | MAPK13 | O15264 | 4/20 | 0.66 |
| ▸ | MAPK12 | P53778 | 4/20 | 0.66 |
| ▸ | MAPK11 | Q15759 | 4/20 | 0.66 |
| ▸ | DDR2 | Q16832 | 3/20 | 0.64 |
| ▸ | CNR1 | P21554 | 1/20 | 0.60 |
| ▸ | CNR2 | P34972 | 1/20 | 0.60 |
| ▸ | TNF | P01375 | 4/20 | 0.58 |
| ▸ | CIT | O14578 | 1/20 | 0.56 |
| ▸ | MUSK | O15146 | 1/20 | 0.56 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.56 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.56 |
| ▸ | STK10 | O94804 | 1/20 | 0.56 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.56 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.56 |
| ▸ | ABL1 | P00519 | 1/20 | 0.56 |
| ▸ | EGFR | P00533 | 1/20 | 0.56 |
| ▸ | RAF1 | P04049 | 1/20 | 0.56 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.56 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4566793 | 1.00 | MAPK14 (0.66) | MAPK14MAPK13MAPK12MAPK11DDR2 | |
| SCHEMBL6334316 | 0.90 | MAPK14 (0.68) | MAPK14MAPK13MAPK12MAPK11DDR2 | |
| SCHEMBL30449051 | 0.90 | MAPK14 (0.68) | MAPK14MAPK13MAPK12MAPK11DDR2 | |
| SCHEMBL4953393 | 0.88 | DDR2 (0.64) | MAPK14MAPK13MAPK12MAPK11DDR2 | |
| SCHEMBL6653980 | 0.88 | MAPK14 (0.66) | MAPK14MAPK13MAPK12MAPK11DDR2 | |
| SCHEMBL10129913 | 0.88 | MAPK14 (0.76) | MAPK14MAPK13MAPK12MAPK11DDR2 | |
| SCHEMBL6401194 | 0.87 | MAPK14 (0.65) | MAPK14MAPK13MAPK12MAPK11DDR2 | |
| SCHEMBL30336428 | 0.86 | MAPK14 (0.53) | MAPK14MAPK13MAPK12MAPK11DDR2 | |
| SCHEMBL5257397 | 0.85 | MAPK14 (0.65) | MAPK14MAPK13MAPK12MAPK11DDR2 | |
| SCHEMBL2787373 | 0.85 | DDR2 (0.61) | MAPK14MAPK13MAPK12MAPK11DDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250302883-A1 | NORMALIZATION OF CULTURE OF CORNEAL ENDOTHELIAL CELLS | KYOTO PREFECTURAL PUBLIC UNIVERSITY CORPORATION (JP) | 2025-10-02 | — | — | US | disclosed |
| EP-4159212-A1 | P38 KINASE INHIBITORS REDUCE DUX4 AND DOWNSTREAM GENE EXPRESSION FOR THE TREATMENT OF FSHD | Fulcrum Therapeutics, Inc. (US) | 2023-04-05 | — | — | EP | disclosed |
| US-20230057984-A1 | NORMALIZATION OF CULTURE OF CORNEAL ENDOTHELIAL CELLS | KYOTO PREFECTURAL PUBLIC UNIVERSITY CORPORATION (JP) | 2023-02-23 | — | — | US | disclosed |
| EP-4041259-A1 | FEEDER-BASED AND FEEDER-FREE STEM CELL CULTURE SYSTEMS FOR STRATIFIED EPITHELIAL STEM CELLS, AND USES RELATED THERETO | University of Houston System (US) | 2022-08-17 | — | — | EP | disclosed |