Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.53 |
| ▸ | CES2 | O00748 | 3/20 | 0.46 |
| ▸ | CES1 | P23141 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 5/20 | 0.45 |
| ▸ | PPARD | Q03181 | 5/20 | 0.45 |
| ▸ | PPARA | Q07869 | 5/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TLR2 | O60603 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | FABP4 | P15090 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27828072 | 0.96 | ACE2 (0.58) | KMT2AMAPTACE2CES2CES1 | |
| SCHEMBL10481199 | 0.94 | ACE2 (0.60) | KMT2AMAPTACE2CES2CES1 | |
| SCHEMBL6859032 | 0.92 | KMT2A (0.55) | KMT2AMAPTACE2CES2CES1 | |
| SCHEMBL11104944 | 0.92 | ACE2 (0.62) | KMT2AMAPTACE2CES2CES1 | |
| SCHEMBL11101881 | 0.90 | ACE2 (0.60) | KMT2AMAPTACE2CES2CES1 | |
| SCHEMBL3411824 | 0.89 | KMT2A (0.52) | KMT2AMAPTACE2CES2CES1 | |
| SCHEMBL6859853 | 0.88 | KMT2A (0.55) | KMT2AMAPTCES2CES1LMNA | |
| SCHEMBL29109637 | 0.88 | ACE2 (0.58) | KMT2AMAPTACE2CES2CES1 | |
| SCHEMBL27685664 | 0.88 | ACE2 (0.58) | KMT2AMAPTACE2CES2CES1 | |
| SCHEMBL31352041 | 0.88 | KMT2A (0.55) | KMT2AMAPTCES2CES1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8230986-B2 | Torque limiter | JTEKT CORPORATION (JP) | 2012-07-31 | — | — | US | disclosed |
| US-8220609-B2 | Torque limiter | JTEKT CORPORATION (JP) | 2012-07-17 | — | — | US | disclosed |
| US-20100184519-A1 | TORQUE LIMITER | JTEKT CORPORATION (JP) | 2010-07-22 | — | — | US | disclosed |