Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.74 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.64 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.60 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.60 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.60 |
| ▸ | RARB | P10826 | 6/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.53 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.53 |
| ▸ | RARA | P10276 | 4/20 | 0.51 |
| ▸ | IKBKB | O14920 | 1/20 | 0.51 |
| ▸ | RARG | P13631 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.47 |
| ▸ | GOT1 | P17174 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30015930 | 0.90 | HDAC11 (0.83) | HDAC11HDAC2HDAC7HDAC8HDAC6 | |
| SCHEMBL22929243 | 0.90 | HDAC11 (0.83) | HDAC11HDAC2HDAC7HDAC8HDAC6 | |
| SCHEMBL29462780 | 0.90 | HDAC11 (0.65) | HDAC11HDAC2HDAC7HDAC8HDAC6 | |
| SCHEMBL30015801 | 0.90 | HDAC11 (0.73) | HDAC11HDAC2HDAC7HDAC8HDAC6 | |
| SCHEMBL30016167 | 0.88 | HDAC11 (0.66) | HDAC11HDAC2HDAC7HDAC8HDAC6 | |
| SCHEMBL30016430 | 0.88 | HDAC11 (0.66) | HDAC11HDAC2HDAC7HDAC8HDAC6 | |
| SCHEMBL405445 | 0.88 | HDAC11 (0.82) | HDAC11HDAC2HDAC7HDAC8HDAC6 | |
| SCHEMBL405444 | 0.88 | HDAC11 (0.82) | HDAC11HDAC2HDAC7HDAC8HDAC6 | |
| SCHEMBL15232880 | 0.87 | HDAC11 (0.64) | HDAC11HDAC2HDAC7HDAC8HDAC6 | |
| SCHEMBL2416033 | 0.87 | HDAC11 (0.64) | HDAC11HDAC2HDAC7HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110114338-B | Retinoid derivatives having antitumor activity | 比奥吉公司 | 2022-10-21 | — | — | CN | disclosed |