Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC11 | Q96DB2 | 6/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | RARB | P10826 | 5/20 | 0.39 |
| ▸ | RARA | P10276 | 3/20 | 0.38 |
| ▸ | IKBKB | O14920 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | RARG | P13631 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30015788 | 0.99 | HDAC11 (0.49) | HDAC11HDAC2HDAC7HDAC8HDAC6 | |
| SCHEMBL30015287 | 0.99 | HDAC11 (0.49) | HDAC11HDAC2HDAC7HDAC8HDAC6 | |
| SCHEMBL29462766 | 0.93 | HDAC11 (0.57) | HDAC11HDAC2HDAC7HDAC8HDAC6 | |
| SCHEMBL30015535 | 0.91 | HDAC11 (0.53) | HDAC11HDAC2HDAC7HDAC8HDAC6 | |
| SCHEMBL30015166 | 0.88 | HDAC11 (0.61) | HDAC11HDAC2HDAC7HDAC8HDAC6 | |
| SCHEMBL20025503 | 0.88 | HDAC11 (0.61) | HDAC11HDAC2HDAC7HDAC8HDAC6 | |
| SCHEMBL23005177 | 0.87 | HDAC11 (0.49) | HDAC11HDAC2HDAC7HDAC8HDAC6 | |
| SCHEMBL30016253 | 0.86 | HDAC11 (0.61) | HDAC11HDAC2HDAC7HDAC8HDAC6 | |
| SCHEMBL23005171 | 0.85 | HDAC11 (0.58) | HDAC11HDAC2HDAC7HDAC8HDAC6 | |
| SCHEMBL22929255 | 0.83 | HDAC11 (0.70) | HDAC11HDAC2HDAC7HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110114338-B | Retinoid derivatives having antitumor activity | 比奥吉公司 | 2022-10-21 | — | — | CN | disclosed |