Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 1/20 | 0.42 |
| ▸ | SYK | P43405 | 2/20 | 0.40 |
| ▸ | PARP1 | P09874 | 3/20 | 0.39 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.37 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.37 |
| ▸ | USP7 | Q93009 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24699445 | 1.00 | ACP1 (0.42) | ACP1SYKPARP1KDM5BHTR7 | |
| SCHEMBL24697803 | 0.99 | ACP1 (0.41) | ACP1SYKPARP1KDM5BHTR7 | |
| SCHEMBL30016293 | 0.99 | ACP1 (0.41) | ACP1SYKPARP1KDM5BHTR7 | |
| SCHEMBL24698791 | 0.98 | ACP1 (0.40) | ACP1SYKPARP1KDM5BHTR7 | |
| SCHEMBL30016307 | 0.92 | LRRK2 (0.42) | PARP1ALDH1A1 | |
| SCHEMBL24698175 | 0.92 | LRRK2 (0.42) | PARP1ALDH1A1 | |
| SCHEMBL30016314 | 0.90 | MTOR (0.42) | ACP1SYKPARP1HTR7EHMT2 | |
| SCHEMBL24698193 | 0.90 | MTOR (0.42) | ACP1SYKPARP1HTR7EHMT2 | |
| SCHEMBL24699012 | 0.88 | MTOR (0.41) | SYKPARP1EHMT2HRH3PRMT6 | |
| SCHEMBL30015464 | 0.88 | MTOR (0.41) | SYKPARP1EHMT2HRH3PRMT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4313967-A1 | KHK INHIBITORS | GILEAD SCIENCES, INC. (US) | 2024-02-07 | — | — | EP | disclosed |
| WO-2022212194-A1 | KHK INHIBITORS | GILEAD SCIENCES, INC. (US) | 2022-10-06 | — | — | WO | disclosed |