Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 20/20 | 0.47 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.47 |
| ▸ | PIK3R1 | P27986 | 4/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22768638 | 0.86 | PIK3CG (0.61) | PIK3CGPIK3CDPIK3R1PIK3CAPIK3CB | |
| SCHEMBL29278897 | 0.86 | PIK3CG (0.61) | PIK3CGPIK3CDPIK3R1PIK3CAPIK3CB | |
| SCHEMBL2028811 | 0.81 | PIK3CG (0.55) | PIK3CGPIK3CDPIK3R1PIK3CAPIK3CB | |
| SCHEMBL2024939 | 0.81 | PIK3CG (0.55) | PIK3CGPIK3CDPIK3R1PIK3CAPIK3CB | |
| SCHEMBL29314052 | 0.74 | PIK3CG (0.59) | PIK3CGPIK3CDPIK3R1PIK3CAPIK3CB | |
| SCHEMBL25865345 | 0.73 | PIK3CG (0.49) | PIK3CGPIK3CDPIK3R1PIK3CAPIK3CB | |
| SCHEMBL29099608 | 0.73 | PIK3CG (0.43) | PIK3CGPIK3CDPIK3R1PIK3CAPIK3CB | |
| SCHEMBL31543989 | 0.73 | PIK3CG (0.43) | PIK3CGPIK3CDPIK3R1PIK3CAPIK3CB | |
| SCHEMBL22768493 | 0.72 | PIK3CG (0.48) | PIK3CGPIK3CDPIK3R1PIK3CAPIK3CB | |
| SCHEMBL22440915 | 0.72 | PIK3CG (0.54) | PIK3CGPIK3CDPIK3R1PIK3CAPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4326260-A1 | PI3K INHIBITORS, NANOFORMULATIONS, AND USES THEREOF | The Regents of The University of Michigan (US) | 2024-02-28 | — | — | EP | disclosed |
| WO-2022226052-A1 | PI3K INHIBITORS, NANOFORMULATIONS, AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2022-10-27 | — | — | WO | disclosed |