Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPA | P38571 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.32 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.32 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2994786 | 0.89 | LIPA (0.35) | LIPAHSD17B10CYP19A1GRIN1GRIN2B | |
| SCHEMBL2999786 | 0.75 | LIPA (0.33) | LIPACDK5CDK5R1NR1I3 | |
| SCHEMBL2994956 | 0.75 | LIPA (0.33) | LIPACDK5CDK5R1NR1I3 | |
| SCHEMBL6941115 | 0.73 | LIPA (0.39) | LIPAHSD17B10CYP19A1CYP11B2 | |
| SCHEMBL1297508 | 0.73 | LIPA (0.39) | LIPAHSD17B10CYP19A1CYP11B2 | |
| SCHEMBL23885014 | 0.73 | LIPA (0.39) | LIPAHSD17B10CYP19A1CYP11B2 | |
| SCHEMBL2049106 | 0.73 | LIPA (0.39) | LIPAHSD17B10CYP19A1CYP11B2 | |
| SCHEMBL6814313 | 0.73 | LIPA (0.39) | LIPAHSD17B10CYP19A1CYP11B2 | |
| SCHEMBL11324326 | 0.73 | LIPA (0.39) | LIPAHSD17B10CYP19A1CYP11B2 | |
| SCHEMBL10452360 | 0.73 | LIPA (0.39) | LIPAHSD17B10CYP19A1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2009304-B1 | TORQUE LIMITER | JTEKT CORP (JP) | 2014-10-01 | — | — | EP | disclosed |
| EP-2003353-B1 | TORQUE LIMITER | JTEKT CORP (JP) | 2014-06-04 | — | — | EP | disclosed |
| US-8230986-B2 | Torque limiter | JTEKT CORPORATION (JP) | 2012-07-31 | — | — | US | disclosed |
| US-8220609-B2 | Torque limiter | JTEKT CORPORATION (JP) | 2012-07-17 | — | — | US | disclosed |
| US-20100184519-A1 | TORQUE LIMITER | JTEKT CORPORATION (JP) | 2010-07-22 | — | — | US | disclosed |
| US-20090173591-A1 | TORQUE LIMITER | JTEKT CORPORATION (JP) | 2009-07-09 | — | — | US | disclosed |
| EP-2009304-A1 | TORQUE LIMITER | JTEKT Corporation (JP) | 2008-12-31 | — | — | EP | disclosed |
| EP-2003353-A1 | TORQUE LIMITER | JTEKT Corporation (JP) | 2008-12-17 | — | — | EP | disclosed |