Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 4/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 6/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | PDE4A | P27815 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30024341 | 0.89 | KMT2A (0.43) | KMT2ATRPA1ADORA2BLMNAPDE4A | |
| SCHEMBL17682211 | 0.83 | KMT2A (0.45) | KMT2ATRPA1ADORA2BLMNAPDE4A | |
| SCHEMBL17682280 | 0.82 | KMT2A (0.48) | KMT2ATRPA1ADORA2BLMNAPDE4A | |
| SCHEMBL17682279 | 0.82 | KMT2A (0.48) | KMT2ATRPA1ADORA2BLMNAPDE4A | |
| SCHEMBL17682249 | 0.82 | KMT2A (0.48) | KMT2ATRPA1ADORA2BLMNAPDE4A | |
| SCHEMBL19601312 | 0.80 | KMT2A (0.50) | KMT2ATRPA1ADORA2BLMNAPDE4A | |
| SCHEMBL17682251 | 0.79 | KMT2A (0.42) | KMT2ATRPA1ADORA2BLMNAPDE4A | |
| SCHEMBL19607674 | 0.78 | KMT2A (0.47) | KMT2ATRPA1ADORA2BLMNAPDE4A | |
| SCHEMBL24611655 | 0.77 | KMT2A (0.46) | KMT2ATRPA1ADORA2BLMNAPDE4A | |
| SCHEMBL17682284 | 0.77 | KMT2A (0.52) | KMT2ATRPA1ADORA2BLMNAPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111233863-B | Hydroxyl purine compound and application thereof | 广东众生睿创生物科技有限公司 | 2022-10-25 | — | — | CN | disclosed |