SCHEMBL3002648

SCHEMBL3002648

CC(C)CCC[C@@H](C)[C@H]1CCC2C3CC=C4CC(Oc5ccc(C6=CC(=O)NC6=O)cc5)CC[C@]4(C)C3CC[C@@]21C

nearest known ligand 0.61

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP46A1 Q9Y6A2 2/20 0.61
POLA1 P09884 1/20 0.61
OSBP P22059 3/20 0.57
USP2 O75604 2/20 0.57
RORC P51449 2/20 0.57
LMNA P02545 1/20 0.57
ABCB1 P08183 1/20 0.57
OSBP2 Q969R2 1/20 0.57
GBA1 P04062 2/20 0.52
UGCG Q16739 2/20 0.52
GBA2 Q9HCG7 2/20 0.52
SRD5A1 P18405 3/20 0.52
NR1H3 Q13133 3/20 0.52
NPC1L1 Q9UHC9 3/20 0.50
GRIN1 Q05586 1/20 0.49
GRIN2A Q12879 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3002643 0.83 CYP46A1 (0.64) CYP46A1POLA1OSBPUSP2RORC
SCHEMBL3003233 0.83 CYP46A1 (0.65) CYP46A1POLA1OSBPUSP2RORC
SCHEMBL3003237 0.83 CYP46A1 (0.65) CYP46A1POLA1OSBPUSP2RORC
SCHEMBL3002110 0.82 CYP46A1 (0.67) CYP46A1POLA1OSBPUSP2RORC
SCHEMBL3002109 0.82 CYP46A1 (0.67) CYP46A1POLA1OSBPUSP2RORC
SCHEMBL105208 0.81 CYP46A1 (0.69) CYP46A1POLA1OSBPUSP2RORC
SCHEMBL17240314 0.81 CYP46A1 (0.69) CYP46A1POLA1OSBPUSP2RORC
SCHEMBL17240315 0.81 CYP46A1 (0.69) CYP46A1POLA1OSBPUSP2RORC
SCHEMBL28232457 0.80 CYP46A1 (0.62) CYP46A1POLA1OSBPUSP2RORC
SCHEMBL23191480 0.80 CYP46A1 (0.76) CYP46A1POLA1OSBPUSP2RORC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7787085-B2 Optical alignment method and liquid crystal display element JSR CORPORATION (JP) 2010-08-31 US disclosed
US-20080123046-A1 OPTICAL ALIGNMENT METHOD AND LIQUID CRYSTAL DISPLAY ELEMENT JSR CORPORATION (JP) 2008-05-29 US disclosed
US-7074344-B2 Liquid crystal aligning agent and liquid crystal display element JSR CORPORATION (JP) 2006-07-11 US disclosed
US-20050259203-A1 Optical alignment method and liquid crystal display element JSR CORPORATION (JP) 2005-11-24 US disclosed
EP-1353217-A1 Optical alignment method and liquid crystal display element JSR Corporation (JP) 2003-10-15 EP disclosed
US-20030087045-A1 Liquid crystal aligning agent and liquid crystal display element JSR CORPORATION (JP) 2003-05-08 US disclosed