SCHEMBL30026569

SCHEMBL30026569

NS(=O)(=O)c1cc(NC(=O)Cc2ccccc2Cl)cc2c(Oc3ccc(F)cc3)nccc12

nearest known ligand 0.56

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
P2RX4 Q99571 20/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23619755 1.00 P2RX4 (0.56) P2RX4
SCHEMBL23619844 0.93 P2RX4 (0.65) P2RX4
SCHEMBL30812868 0.93 P2RX4 (0.65) P2RX4
SCHEMBL30812830 0.92 P2RX4 (0.58) P2RX4
SCHEMBL23619834 0.92 P2RX4 (0.58) P2RX4
SCHEMBL30812801 0.92 P2RX4 (0.56) P2RX4
SCHEMBL23619839 0.92 P2RX4 (0.56) P2RX4
SCHEMBL24713540 0.89 P2RX4 (0.45) P2RX4
SCHEMBL23619625 0.89 P2RX4 (0.58) P2RX4
SCHEMBL23619957 0.87 P2RX4 (0.56) P2RX4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114901642-B Fused ring compound and application thereof 武汉朗来科技发展有限公司 2024-02-23 CN disclosed
EP-4079724-A1 FUSED RING COMPOUND AND APPLICATION THEREOF Wuhan LL Science and Technology Development Co., Ltd. (CN) 2022-10-26 EP disclosed