Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.68 |
| ▸ | FERMT2 | Q96AC1 | 4/20 | 0.65 |
| ▸ | MAPT | P10636 | 4/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | CCR1 | P32246 | 1/20 | 0.64 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | KMT5B | Q4FZB7 | 1/20 | 0.59 |
| ▸ | KMT5C | Q86Y97 | 1/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2455864 | 1.00 | CYP1A2 (0.68) | CYP1A2FERMT2MAPTTDP1KMT2A | |
| Hydrochloric Acid SCHEMBL5680197 | 0.98 | CYP1A2 (0.66) | CYP1A2FERMT2MAPTTDP1KMT2A | |
| SCHEMBL2477414 | 0.86 | NR4A2 (0.61) | CYP1A2FERMT2MAPTTDP1KMT2A | |
| SCHEMBL23904649 | 0.82 | CYP1A2 (0.68) | CYP1A2FERMT2MAPTTDP1KMT2A | |
| SCHEMBL12840976 | 0.82 | CYP1A2 (0.68) | CYP1A2FERMT2MAPTTDP1KMT2A | |
| SCHEMBL12223738 | 0.81 | FERMT2 (0.78) | CYP1A2FERMT2MAPTTDP1KMT2A | |
| SCHEMBL8738060 | 0.81 | CYP1A2 (1.00) | CYP1A2FERMT2KMT2ACCR1NR4A2 | |
| SCHEMBL729361 | 0.81 | MAPT (0.71) | CYP1A2FERMT2MAPTTDP1KMT2A | |
| SCHEMBL1147519 | 0.79 | FERMT2 (1.00) | CYP1A2FERMT2KMT2ACCR1NR4A2 | |
| SCHEMBL3398399 | 0.79 | NR4A2 (0.76) | CYP1A2FERMT2MAPTTDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230109016-A1 | IN-VITRO DIAGNOSIS OF HISTAMINE INTOLERANCE SYNDROME | IMMUNDIAGNOSTIK AG (DE) | 2023-04-06 | — | — | US | claimed |
| EP-4103946-A1 | IN-VITRO DIAGNOSIS OF HISTAMINE INTOLERANCE SYNDROME | Immundiagnostik AG (DE) | 2022-12-21 | — | — | EP | claimed |
| EP-4398902-A1 | COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS COMPRISING INHIBITORS OF AMYLOID PEPTIDE INTERACTIONS WITH GLYCOSAMINOGLYCANS, METHODS OF TREATMENT, AND USE THEREOF | Gismo Therapeutics, Inc. (US) | 2024-07-17 | — | — | EP | disclosed |
| WO-2023038876-A1 | COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS COMPRISING INHIBITORS OF AMYLOID PEPTIDE INTERACTIONS WITH GLYCOSAMINOGLYCANS, METHODS OF TREATMENT, AND USE THEREOF | GISMO THERAPEUTICS, INC. (US) | 2023-03-16 | — | — | WO | disclosed |