SCHEMBL30029486

SCHEMBL30029486

N=C(N)NCCC[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](N)CCCCN)C(N)=O

nearest known ligand 0.52

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ NPY4R P50391 13/20 0.52
▸ NPY1R P25929 8/20 0.52
▸ NPY2R P49146 6/20 0.52
▸ NPY5R Q15761 6/20 0.52
▸ OPRM1 P35372 1/20 0.44
▸ TLR2 O60603 1/20 0.43
▸ GNAI3 P08754 1/20 0.41
▸ GNAO1 P09471 1/20 0.41
▸ GNAI1 P63096 1/20 0.41
▸ SIRT5 Q9NXA8 1/20 0.40
▸ ROCK2 O75116 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30028934 1.00 NPY4R (0.52) NPY4RNPY1RNPY2RNPY5ROPRM1
SCHEMBL30028687 1.00 NPY4R (0.52) NPY4RNPY1RNPY2RNPY5ROPRM1
SCHEMBL30029283 1.00 NPY4R (0.52) NPY4RNPY1RNPY2RNPY5ROPRM1
SCHEMBL29476450 1.00 NPY4R (0.52) NPY4RNPY1RNPY2RNPY5ROPRM1
SCHEMBL30787063 1.00 NPY4R (0.52) NPY4RNPY1RNPY2RNPY5ROPRM1
SCHEMBL30787051 1.00 NPY4R (0.52) NPY4RNPY1RNPY2RNPY5ROPRM1
SCHEMBL29476470 1.00 NPY4R (0.52) NPY4RNPY1RNPY2RNPY5ROPRM1
SCHEMBL30029319 1.00 NPY4R (0.52) NPY4RNPY1RNPY2RNPY5ROPRM1
SCHEMBL30029277 1.00 NPY4R (0.52) NPY4RNPY1RNPY2RNPY5ROPRM1
SCHEMBL29476500 1.00 NPY4R (0.52) NPY4RNPY1RNPY2RNPY5ROPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220339239-A1 USE OF MELANOCORTINS TO TREAT INSULIN SENSITIVITY IPSEN PHARMA SAS (FR) 2022-10-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220339239-A1 USE OF MELANOCORTINS TO TREAT INSULIN SENSITIVITY MC4R, MC1R, MC3R NPY4R 7/4885NPY1R 18/4885NPY2R 19/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback