SCHEMBL30030218

SCHEMBL30030218

CCC1(O)C(=O)OCc2c1cc1n(c2=O)Cc2c-1nc1cc3c(cc1c2CCCNC(=O)CN)OCO3

nearest known ligand 0.74

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ TOP1 P11387 19/20 0.74
▸ SLC2A1 P11166 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24642863 1.00 TOP1 (0.74) TOP1SLC2A1
SCHEMBL31289333 0.92 TOP1 (0.70) TOP1SLC2A1
SCHEMBL24642405 0.92 TOP1 (0.70) TOP1SLC2A1
SCHEMBL21450505 0.92 TOP1 (0.78) TOP1SLC2A1
SCHEMBL31324791 0.90 TOP1 (0.82) TOP1SLC2A1
SCHEMBL24642715 0.90 TOP1 (0.82) TOP1SLC2A1
SCHEMBL26520548 0.90 TOP1 (0.70) TOP1SLC2A1
SCHEMBL24642392 0.90 TOP1 (0.62) TOP1
SCHEMBL30030222 0.90 TOP1 (0.62) TOP1
SCHEMBL26108847 0.89 TOP1 (0.72) TOP1SLC2A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119564878-A Bioactive substance conjugate, preparation method and application thereof 苏州宜联生物医药有限公司 2025-03-07 — — CN disclosed
CN-119504997-A Bioactive substance conjugate, preparation method and application thereof 苏州宜联生物医药有限公司 2025-02-25 — — CN disclosed
CN-119497631-A Antibody drug conjugate, preparation method and application thereof 苏州宜联生物医药有限公司 2025-02-21 — — CN disclosed
CN-119486763-A Antibody drug conjugate, preparation method and application thereof 苏州宜联生物医药有限公司 2025-02-18 — — CN disclosed
CN-115279417-B Bioactive substance conjugate, preparation method and application thereof 苏州宜联生物医药有限公司 2025-01-03 — — CN disclosed
CN-115279417-A Bioactive substance conjugate and preparation method and application thereof 苏州宜联生物医药有限公司 2022-11-01 — — CN disclosed
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