⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30030844 | 1.00 | — | — | |
| SCHEMBL30032164 | 1.00 | — | — | |
| SCHEMBL30031286 | 0.92 | — | — | |
| SCHEMBL30030847 | 0.92 | — | — | |
| SCHEMBL30031614 | 0.92 | — | — | |
| SCHEMBL30031721 | 0.90 | KDM4E (0.32) | — | |
| SCHEMBL30031695 | 0.90 | KDM4E (0.32) | — | |
| SCHEMBL30031950 | 0.90 | KDM4E (0.32) | — | |
| SCHEMBL30031474 | 0.87 | IDH1 (0.31) | — | |
| SCHEMBL30031308 | 0.87 | IDH1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022214937-A1 | SUBSTITUTED TETRACYCLIC CARBOXYLIC ACIDS, ANALOGUES THEREOF, AND METHODS USING SAME | ARBUTUS BIOPHARMA CORPORATION (CA) | 2022-10-13 | — | — | WO | claimed |
| WO-2022214937-A1 | SUBSTITUTED TETRACYCLIC CARBOXYLIC ACIDS, ANALOGUES THEREOF, AND METHODS USING SAME | ARBUTUS BIOPHARMA CORPORATION (CA) | 2022-10-13 | — | — | WO | disclosed |