Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | AKT2 | P31751 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30031474 | 0.92 | IDH1 (0.31) | — | |
| SCHEMBL30031308 | 0.92 | IDH1 (0.31) | — | |
| SCHEMBL30031721 | 0.92 | KDM4E (0.32) | KDM4EALDH1A1POLBGAA | |
| SCHEMBL30031950 | 0.92 | KDM4E (0.32) | KDM4EALDH1A1POLBGAA | |
| SCHEMBL30031695 | 0.92 | KDM4E (0.32) | KDM4EALDH1A1POLBGAA | |
| SCHEMBL30030840 | 0.92 | IDH1 (0.31) | — | |
| SCHEMBL30031847 | 0.89 | KDM4E (0.33) | KDM4EALDH1A1POLBGAA | |
| SCHEMBL30032609 | 0.89 | KDM4E (0.33) | KDM4EALDH1A1POLBGAA | |
| SCHEMBL30032232 | 0.89 | KDM4E (0.33) | KDM4EALDH1A1POLBGAA | |
| SCHEMBL30031286 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022214937-A1 | SUBSTITUTED TETRACYCLIC CARBOXYLIC ACIDS, ANALOGUES THEREOF, AND METHODS USING SAME | ARBUTUS BIOPHARMA CORPORATION (CA) | 2022-10-13 | — | — | WO | disclosed |