Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 7/20 | 0.32 |
| ▸ | RBP4 | P02753 | 6/20 | 0.32 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | USP7 | Q93009 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30032273 | 1.00 | NR1H2 (0.33) | NR1H2NR1H3RORCRBP4UCHL1 | |
| SCHEMBL30032126 | 1.00 | NR1H2 (0.33) | NR1H2NR1H3RORCRBP4UCHL1 | |
| SCHEMBL30030851 | 0.87 | — | — | |
| SCHEMBL30031814 | 0.87 | — | — | |
| SCHEMBL30032003 | 0.87 | — | — | |
| SCHEMBL24357019 | 0.86 | KDM4E (0.32) | UCHL1 | |
| SCHEMBL30032007 | 0.85 | KMT2A (0.33) | — | |
| SCHEMBL30030923 | 0.85 | KMT2A (0.33) | — | |
| SCHEMBL30031347 | 0.85 | KMT2A (0.33) | — | |
| SCHEMBL24357108 | 0.85 | HCRTR2 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022214937-A1 | SUBSTITUTED TETRACYCLIC CARBOXYLIC ACIDS, ANALOGUES THEREOF, AND METHODS USING SAME | ARBUTUS BIOPHARMA CORPORATION (CA) | 2022-10-13 | — | — | WO | disclosed |