Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 4/20 | 0.62 |
| ▸ | HTR2C | P28335 | 2/20 | 0.58 |
| ▸ | BCDIN3D | Q7Z5W3 | 9/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23579838 | 1.00 | PDE5A (0.62) | PDE5AHTR2CBCDIN3DTP53MAPT | |
| SCHEMBL23580247 | 0.92 | BCDIN3D (0.65) | PDE5AHTR2CBCDIN3DMAPT | |
| SCHEMBL30033469 | 0.87 | CA1 (0.60) | HTR2CBCDIN3DMAPT | |
| SCHEMBL23579931 | 0.87 | CA1 (0.60) | HTR2CBCDIN3DMAPT | |
| SCHEMBL23579807 | 0.86 | CA1 (0.62) | HTR2CBCDIN3DMAPT | |
| SCHEMBL30034104 | 0.84 | BCDIN3D (0.57) | PDE5AHTR2CBCDIN3DTP53MAPT | |
| SCHEMBL23580265 | 0.84 | BCDIN3D (0.56) | BCDIN3DMAPT | |
| SCHEMBL23579582 | 0.84 | BCDIN3D (0.57) | PDE5AHTR2CBCDIN3DTP53MAPT | |
| SCHEMBL23579870 | 0.82 | BCDIN3D (0.52) | HTR2CBCDIN3DMAPT | |
| SCHEMBL23579698 | 0.82 | PDE2A (0.55) | HTR2CBCDIN3DTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115151550-B | External nucleotide pyrophosphatase/phosphodiesterase 1 (ENPP 1) modulators and uses thereof | 桑福德·伯纳姆·普雷比医学发现研究所 | 2024-11-22 | — | — | CN | disclosed |
| EP-4081528-A1 | ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE 1 (ENPP1) MODULATORS AND USES THEREOF | Sanford Burnham Prebys Medical Discovery Institute (US) | 2022-11-02 | — | — | EP | disclosed |