Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 16/20 | 0.57 |
| ▸ | MAP2K2 | P36507 | 3/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20565269 | 1.00 | MAP2K1 (0.57) | MAP2K1MAP2K2CYP2C9KCNH2CYP2C19 | |
| SCHEMBL22045822 | 0.91 | MAP2K1 (0.58) | MAP2K1MAP2K2CYP2C9KCNH2CYP2C19 | |
| SCHEMBL30034176 | 0.90 | MAP2K1 (0.56) | MAP2K1MAP2K2CYP2C9KCNH2CYP2C19 | |
| SCHEMBL20565325 | 0.90 | MAP2K1 (0.56) | MAP2K1MAP2K2CYP2C9KCNH2CYP2C19 | |
| SCHEMBL24088798 | 0.89 | MAP2K1 (0.47) | MAP2K1MAP2K2CYP2C9KCNH2CYP2C19 | |
| SCHEMBL20565262 | 0.87 | MAP2K1 (0.57) | MAP2K1MAP2K2CYP2C9KCNH2CYP2C19 | |
| SCHEMBL30034530 | 0.87 | MAP2K1 (0.57) | MAP2K1MAP2K2CYP2C9KCNH2CYP2C19 | |
| SCHEMBL20565703 | 0.83 | MAP2K1 (0.55) | MAP2K1MAP2K2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL30034958 | 0.83 | MAP2K1 (0.55) | MAP2K1MAP2K2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL24906390 | 0.83 | MAP2K1 (0.48) | MAP2K1MAP2K2CYP2C9KCNH2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119215031-A | Arylaniline and heteroaryl aniline compounds for the treatment of skin cancer | 恩福莱克逊治疗有限公司 | 2024-12-31 | — | — | CN | disclosed |
| CN-113645964-B | Arylaniline and heteroaryl aniline compounds for fetal treatment | 恩福莱克逊治疗有限公司 | 2024-10-11 | — | — | CN | disclosed |
| CN-113660931-B | Arylaniline and heteroaryl aniline compounds for the treatment of skin cancer | 恩福莱克逊治疗有限公司 | 2024-10-11 | — | — | CN | disclosed |
| CN-111093658-B | Fused heteroaromatic-aniline compounds for the treatment of skin diseases | 恩福莱克逊治疗有限公司 | 2022-10-14 | — | — | CN | disclosed |