Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 16/20 | 0.49 |
| ▸ | MAP2K2 | P36507 | 9/20 | 0.49 |
| ▸ | FLT1 | P17948 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20564882 | 1.00 | MAP2K1 (0.49) | MAP2K1MAP2K2FLT1HDAC3HDAC1 | |
| SCHEMBL24350597 | 0.89 | DHODH (0.46) | MAP2K1MAP2K2SHMT2 | |
| SCHEMBL29536268 | 0.88 | MAP2K1 (0.41) | MAP2K1MAP2K2FLT1HDAC3HDAC1 | |
| SCHEMBL28410513 | 0.88 | MAP2K1 (0.41) | MAP2K1MAP2K2FLT1HDAC3HDAC1 | |
| SCHEMBL20565321 | 0.86 | MAP2K1 (0.51) | MAP2K1MAP2K2HDAC3HDAC1HDAC6 | |
| SCHEMBL30035390 | 0.86 | MAP2K1 (0.51) | MAP2K1MAP2K2HDAC3HDAC1HDAC6 | |
| SCHEMBL30034176 | 0.85 | MAP2K1 (0.56) | MAP2K1MAP2K2 | |
| SCHEMBL20565325 | 0.85 | MAP2K1 (0.56) | MAP2K1MAP2K2 | |
| SCHEMBL20565259 | 0.81 | MAP2K1 (0.48) | MAP2K1MAP2K2FLT1HDAC3HDAC1 | |
| SCHEMBL30035345 | 0.81 | MAP2K1 (0.48) | MAP2K1MAP2K2FLT1HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119215031-A | Arylaniline and heteroaryl aniline compounds for the treatment of skin cancer | 恩福莱克逊治疗有限公司 | 2024-12-31 | — | — | CN | disclosed |
| CN-113645964-B | Arylaniline and heteroaryl aniline compounds for fetal treatment | 恩福莱克逊治疗有限公司 | 2024-10-11 | — | — | CN | disclosed |
| CN-113660931-B | Arylaniline and heteroaryl aniline compounds for the treatment of skin cancer | 恩福莱克逊治疗有限公司 | 2024-10-11 | — | — | CN | disclosed |
| CN-111093658-B | Fused heteroaromatic-aniline compounds for the treatment of skin diseases | 恩福莱克逊治疗有限公司 | 2022-10-14 | — | — | CN | disclosed |