SCHEMBL30037151

SCHEMBL30037151

Cc1ccccc1C(=O)N(C)C

nearest known ligand 0.66

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.59
SMN1; SMN2 Q16637 4/20 0.57
MEN1 O00255 2/20 0.57
TSHR P16473 2/20 0.51
MAPK1 P28482 1/20 0.51
KEAP1 Q14145 1/20 0.50
HPGD P15428 3/20 0.47
ERCC5 P28715 1/20 0.46
FEN1 P39748 1/20 0.46
HTT P42858 1/20 0.44
ALDH1A1 P00352 1/20 0.43
TP53 P04637 1/20 0.43
GAA P10253 1/20 0.43
MAPT P10636 1/20 0.43
NPC1 O15118 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL354228 1.00 KMT2A (0.59) KMT2ASMN1; SMN2MEN1TSHRMAPK1
Hydrochloric Acid SCHEMBL1776796 0.98 KMT2A (0.58) KMT2ASMN1; SMN2MEN1TSHRMAPK1
SCHEMBL28248149 0.90 KMT2A (0.51) KMT2ASMN1; SMN2MEN1TSHRMAPK1
SCHEMBL28068523 0.87 KMT2A (0.53) KMT2ASMN1; SMN2MEN1TSHRMAPK1
SCHEMBL11216342 0.86 KMT2A (0.59) KMT2ASMN1; SMN2MEN1TSHRMAPK1
SCHEMBL188296 0.85 MEN1 (0.65) KMT2ASMN1; SMN2MEN1TSHRKEAP1
SCHEMBL29845658 0.85 KMT2A (0.50) KMT2ASMN1; SMN2MEN1TSHRMAPK1
SCHEMBL3634403 0.84 KMT2A (0.58) KMT2ASMN1; SMN2MEN1TSHRMAPK1
SCHEMBL3760396 0.84 KMT2A (0.65) KMT2ASMN1; SMN2MEN1TSHRMAPK1
SCHEMBL1810392 0.83 ESR1 (0.59) KMT2ASMN1; SMN2MEN1TSHRKEAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022250885-A2 ETHYLENE OLIGOMERIZATION PROCESSES CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2022-12-01 WO disclosed